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慢性十二指肠溃疡患者液体胃排空模式异常。

Abnormal pattern of gastric emptying of liquid in chronic duodenal ulcer.

作者信息

Parr N J, Grime S, Critchley M, Baxter J N, Mackie C R

机构信息

University Department of Surgery, Royal Liverpool Hospital, UK.

出版信息

Digestion. 1988;40(4):237-43. doi: 10.1159/000199660.

DOI:10.1159/000199660
PMID:3234630
Abstract

Gastric emptying was measured in 12 patients with chronic duodenal ulceration and compared with the results from 10 healthy volunteers. The test meal of 300 ml 15% dextrose, labelled with 99mTc-DTPA, was ingested in increments over 6 min. Gamma camera imaging proceeded over 30 min, with a 1-min frame time. A direct correction was applied for the fraction emptying into the small bowel during the ingestion period. Gastric emptying at 6 min was significantly greater in the group with duodenal ulcer (14.4 +/- 2.7% vs. 4.2 +/- 0.9%: mean +/- SEM, p less than 0.01). From this time onwards there were no significant differences in the rates of gastric emptying. These results suggest that chronic duodenal ulcer is associated with an abnormal pattern of gastric emptying of liquid, characterised by an initial rapid phase.

摘要

对12例慢性十二指肠溃疡患者进行了胃排空测量,并与10名健康志愿者的结果进行比较。300毫升15%葡萄糖的试验餐用99mTc-DTPA标记,在6分钟内分次摄入。γ相机成像持续30分钟,帧时间为1分钟。对摄入期间排入小肠的排空分数进行了直接校正。十二指肠溃疡组6分钟时的胃排空明显更大(14.4±2.7%对4.2±0.9%:平均值±标准误,p<0.01)。从此时起,胃排空率没有显著差异。这些结果表明,慢性十二指肠溃疡与液体胃排空的异常模式有关,其特征是初始快速期。

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