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短期翻修风险高:八项大型关节置换登记研究分析髌股关节炎假体置换

Short-term Revision Risk of Patellofemoral Arthroplasty Is High: An Analysis from Eight Large Arthroplasty Registries.

机构信息

P. L. Lewis, M. Lorimer, Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR), Adelaide, Australia.

P. L. Lewis, Lund University, Faculty of Medicine, Clinical Sciences Lund, Dept. of Orthopedics, Lund, Sweden.

出版信息

Clin Orthop Relat Res. 2020 Jun;478(6):1222-1231. doi: 10.1097/CORR.0000000000001268.

Abstract

BACKGROUND

Patellofemoral arthroplasty (PFA) is one option for the treatment of isolated patellofemoral osteoarthritis, but there are limited data regarding the procedure and results. Because isolated patellofemoral arthritis is relatively uncommon, available case series generally are small, and even within national registries, sample sizes are limited. Combining data from multiple registries may aid in assessing worldwide PFA usage and survivorship.

QUESTIONS/PURPOSES: We combined and compared data from multiple large arthroplasty registries worldwide to ask: (1) What proportion of patients undergoing primary knee arthroplasty have PFA? (2) What are the patient and prosthesis characteristics associated with PFA in common practice, as reflected in registries? (3) What is the survivorship free from revision of PFA and what are the reasons for and types of revisions?

METHODS

Data were provided by eight registries that are members of the International Society of Arthroplasty Registries (ISAR) who agreed to share aggregate data: Australia, New Zealand, Canada, Sweden, Finland, Norway, the Netherlands, and the United States. De-identified data were obtained for PFA performed from either the beginning of year 2000, or the earliest recorded implantation date after that in each individual registry when PFA data collection commenced, up to December 31, 2016. This included patient demographics, implant use, all-cause revision rate (determined by cumulative percent revision [CPR]), and reasons for and type of revision.

RESULTS

During the data collection period, 6784 PFAs were performed in the eight countries. PFAs comprised less than 1% of primary knee replacements in all registries. Patient demographics were comparable in all countries. Patients were generally more likely to be women than men, and the mean age ranged from 50 years to 60 years. All registries showed a high rate of revision for PFA. The 5-year CPR for any reason ranged from 8.0% (95% CI 4.5 to 11.5) in Norway to 18.1% (95% CI 15.5 to 20.7) in the Netherlands. The most common reason for revision across all countries was disease progression (42%, 434 of 1034). Most PFAs (83%, 810 of 980) were revised to a TKA.

CONCLUSIONS

The revision risk of PFA in all registries surveyed was more than three times higher than the reported revision risk of TKA at the same times. The survivorship of PFA is similar to that of the no-longer-used procedure of metal-on-metal conventional hip replacement. Although there may be potential functional benefits from PFA, these findings of consistent and alarmingly high rates of revision should create concern, particularly as this procedure is often used in younger patients.

LEVEL OF EVIDENCE

Level III, therapeutic study.

摘要

背景

髌股关节置换术(PFA)是治疗孤立性髌股关节炎的一种选择,但关于该手术的程序和结果的数据有限。由于孤立性髌股关节炎相对少见,可用的病例系列通常较小,即使在国家注册中心内,样本量也有限。合并来自多个注册中心的数据可能有助于评估全球范围内 PFA 的使用情况和生存率。

问题/目的:我们合并并比较了来自全球多个大型关节置换注册中心的数据,以提出以下问题:(1)接受初次膝关节置换的患者中,有多少人接受了 PFA?(2)在注册中心反映的常见实践中,哪些患者和假体特征与 PFA 相关?(3)PFA 的无翻修生存率是多少,翻修的原因和类型是什么?

方法

来自国际关节置换注册协会(ISAR)的 8 个注册中心的成员同意共享汇总数据,这些注册中心提供了数据:澳大利亚、新西兰、加拿大、瑞典、芬兰、挪威、荷兰和美国。从每个注册中心开始收集 PFA 数据的年初或最早记录的植入日期(2000 年)起,至 2016 年 12 月 31 日,获得了 PFA 手术的去标识数据。这包括患者人口统计学、植入物使用情况、全因翻修率(通过累积百分比翻修[CPR]确定)以及翻修的原因和类型。

结果

在数据收集期间,8 个国家共进行了 6784 例 PFA。在所有注册中心,PFA 不到初次膝关节置换的 1%。所有国家的患者人口统计学特征相似。患者通常以女性居多,平均年龄在 50 岁至 60 岁之间。所有注册中心的 PFA 翻修率都很高。任何原因的 5 年 CPR 范围从挪威的 8.0%(95%CI 4.5 至 11.5)到荷兰的 18.1%(95%CI 15.5 至 20.7)。所有国家中最常见的翻修原因是疾病进展(42%,1034 例中有 434 例)。大多数 PFA(83%,810 例中的 810 例)被翻修为 TKA。

结论

所有接受调查的注册中心中,PFA 的翻修风险都高于同时期报告的 TKA 翻修风险的三倍以上。PFA 的生存率与已不再使用的金属对金属传统髋关节置换术相似。尽管 PFA 可能具有潜在的功能益处,但这些一致且令人震惊的高翻修率的发现应引起关注,特别是因为该手术通常用于年轻患者。

证据水平

三级,治疗性研究。

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