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从关节置换术返修率最低的髋关节置换术(THA)和膝关节置换术(TKA)医生身上,我们能学到什么?来自澳大利亚矫形协会全国关节置换登记处的研究。

What Can We Learn From Surgeons Who Perform THA and TKA and Have the Lowest Revision Rates? A Study from the Australian Orthopaedic Association National Joint Replacement Registry.

机构信息

Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Parkville, Australia.

Traumaplasty Melbourne, East Melbourne, Australia.

出版信息

Clin Orthop Relat Res. 2022 Mar 1;480(3):464-481. doi: 10.1097/CORR.0000000000002007.

Abstract

BACKGROUND

Long-term implant survivorship in THA and TKA involves a combination of factors related to the patient, the implants used, and the decision-making and technical performance of the surgeon. It is unclear which of these factors is the most important in reducing the proportion of revision surgery.

QUESTIONS/PURPOSES: We used data from a large national registry to ask: In patients receiving primary THA and TKA for a diagnosis of osteoarthritis, do (1) the reasons for revision and (2) patient factors, the implants used, and the surgeon or surgical factors differ between surgeons performing THA and TKA who have a lower revision rate compared with all other surgeons?

METHODS

Data were analyzed for all THA and TKA procedures performed for a diagnosis of osteoarthritis from the Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR) from September 1, 1999, when collection began, to December 31, 2018. The AOANJRR obtains data on more than 98% of joint arthroplasties performed in Australia. The 5-year cumulative percent revision (CPR) was identified for all THAs and TKAs performed for a diagnosis of osteoarthritis with 95% confidence intervals (overall CPR); the 5-year CPR with 95% CIs for each surgeon was calculated for THA and TKA separately. For surgeons to be included in the analysis, they had to have performed at least 50 procedures and have a 5-year CPR. The 5-year CPR with 95% CIs for each THA and TKA surgeon was compared with the overall CPR. Two groups were defined: low revision rate surgeons (the upper confidence level for a given surgeon at 5 years is less than 3.84% for THA and 4.32% for TKA), and all other surgeons (any surgeon whose CPR was higher than those thresholds). The thresholds were determined by setting a cutoff at 20% above the upper confidence level for that class. The approach we used to define a low revision rate surgeon was similar to that used by the AOANJRR for determining the better-performing prostheses and is recommended by the International Prosthesis Benchmarking Working Group. By defining the groups in this way, a significant difference between these two groups is created. Determining a reason for this difference is the purpose of presenting the proportions of different factors within each group. The study group for THA included 116 low revision rate surgeons, who performed 88,392 procedures (1619 revised, 10-year CPR 2.7% [95% CI 2.6% to 2.9%]) and 433 other surgeons, who performed 170,094 procedures (6911 revised, 10-year CPR 5.9% [95% CI 5.7% to 6.0%]). The study group for TKA consisted of 144 low revision rate surgeons, who performed 159,961 procedures (2722 revised, 10-year CPR 2.6% [95% CI 2.5% to 2.8%]) and 534 other surgeons, who performed 287,232 procedures (12,617 revised, 10-year CPR 6.4% [95% CI 6.3% to 6.6%]). These groups were defined a priori by their rate of revision, and the purpose of this study was to explore potential reasons for this observed difference.

RESULTS

For THA, the difference in overall revision rate between low revision rate surgeons and other surgeons was driven mainly by fewer revisions for dislocation, followed by component loosening and fracture in patients treated by low revision rate surgeons. For TKA, the difference in overall revision rate between low revision rate surgeons and other surgeons was driven mainly by fewer revisions for aseptic loosening, followed by instability and patellofemoral complications in patients treated by low revision rate surgeons. Patient-related factors were generally similar between low revision rate surgeons and other surgeons for both THA and TKA. Regarding THA, there were differences in implant factors, with low revision rate surgeons using fewer types of implants that have been identified as having a higher-than-anticipated rate of revision within the AOANJRR. Low revision rate surgeons used a higher proportion of hybrid fixation, although cementless fixation remained the most common choice. For surgeon factors, low revision rate surgeons were more likely to perform more than 100 THA procedures per year, while other surgeons were more likely to perform fewer than 50 THA procedures per year. In general, the groups of surgeons (low revision rate surgeons and other surgeons) differed less in terms of years of surgical experience than they did in terms of the number of cases they performed each year, although low revision rate surgeons, on average, had more years of experience and performed more cases per year. Regarding TKA, there were more differences in implant factors than with THA, with low revision rate surgeons more frequently performing patellar resurfacing, using an AOANJRR-identified best-performing prosthesis combination (with the lowest rates of revision), using fewer implants that have been identified as having a higher-than-anticipated rate of revision within the AOANJRR, using highly crosslinked polyethylene, and using a higher proportion of cemented fixation compared with other surgeons. For surgeon factors, low revision rate surgeons were more likely to perform more than 100 TKA procedures per year, whereas all other surgeons were more likely to perform fewer than 50 procedures per year. Again, generally, the groups of surgeons (low revision rate surgeons and other surgeons) differed less in terms of years of surgical experience than they did in terms of the number of cases they performed annually, although low revision rate surgeons, on average, had more years of experience and performed more cases per year.

CONCLUSION

THAs and TKAs performed by surgeons with the lowest revision rates in Australia show reductions in all of the leading causes of revision for both THA and TKA, in particular, causes of revision related to the technical performance of these procedures. Patient factors were similar between low revision rate surgeons and all other surgeons for both THA and TKA. Low revision rate THA surgeons were more likely to use cement fixation selectively. Low revision rate TKA surgeons were more likely to use patella resurfacing, crosslinked polyethylene, and cemented fixation. Low revision rate THA and TKA surgeons were more likely to use an AOANJRR-identified best-performing prosthesis combination and to use fewer implants identified by the AOANJRR as having a higher-than-anticipated revision rate. To reduce the rate of revision THA and TKA, surgeons should consider addressing modifiable factors related to implant selection. Future research should identify surgeon factors beyond annual case volume that are important to improving implant survivorship.

LEVEL OF EVIDENCE

Level III, therapeutic study.

摘要

背景

全髋关节置换术(THA)和全膝关节置换术(TKA)的长期假体存活率涉及与患者、使用的假体以及外科医生的决策和技术表现相关的多个因素。尚不清楚这些因素中哪一个在降低翻修手术比例方面最重要。

问题/目的:我们使用来自大型全国登记处的数据,询问在因骨关节炎接受初次 THA 和 TKA 的患者中,(1)翻修原因和(2)患者因素、使用的假体以及外科医生或手术因素,在与所有其他外科医生相比,具有较低翻修率的 THA 和 TKA 外科医生之间是否存在差异?

方法

从 1999 年 9 月 1 日(收集开始时)至 2018 年 12 月 31 日,对澳大利亚矫形协会全国关节置换登记处(AOANJRR)中因骨关节炎接受初次 THA 和 TKA 的所有手术进行了分析。AOANJRR 获得了澳大利亚进行的超过 98%的关节置换术的数据。使用 95%置信区间(整体翻修率(CPR))确定了所有因骨关节炎接受初次 THA 和 TKA 的患者的 5 年累积翻修率(CPR);分别为 THA 和 TKA 计算了每位外科医生的 5 年 CPR。为了纳入分析,外科医生必须至少进行了 50 例手术,并且 5 年 CPR 必须达到规定的标准。将每位 THA 和 TKA 外科医生的 5 年 CPR 与整体 CPR 进行比较。将外科医生分为两组:低翻修率外科医生(给定外科医生在 5 年内的置信上限为 THA 低于 3.84%,TKA 低于 4.32%)和所有其他外科医生(CPR 高于这些阈值的任何外科医生)。通过将截止值设定在该类别的置信上限的 20%以上来确定截止值。我们定义低翻修率外科医生的方法与 AOANJRR 用于确定表现更好的假体的方法类似,并且也得到了国际假体基准工作组的推荐。通过以这种方式定义低翻修率外科医生,可以在这两组之间创建显著差异。确定这种差异的原因是展示每组内不同因素的比例的目的。THA 的研究组包括 116 名低翻修率外科医生,他们进行了 88392 例手术(1619 例翻修,10 年 CPR 为 2.7%[95%CI 2.6%至 2.9%])和 433 名其他外科医生,他们进行了 170094 例手术(6911 例翻修,10 年 CPR 为 5.9%[95%CI 5.7%至 6.0%])。TKA 的研究组包括 144 名低翻修率外科医生,他们进行了 159961 例手术(2722 例翻修,10 年 CPR 为 2.6%[95%CI 2.5%至 2.8%])和 534 名其他外科医生,他们进行了 287232 例手术(12617 例翻修,10 年 CPR 为 6.4%[95%CI 6.3%至 6.6%])。这些组是根据其翻修率预先定义的,本研究的目的是探讨观察到的差异的潜在原因。

结果

对于 THA,低翻修率外科医生和其他外科医生之间的总体翻修率差异主要归因于低翻修率外科医生的脱位、组件松动和骨折翻修率较低。对于 TKA,低翻修率外科医生和其他外科医生之间的总体翻修率差异主要归因于低翻修率外科医生的无菌性松动、不稳定和髌股并发症翻修率较低。THA 和 TKA 的患者相关因素在低翻修率外科医生和其他外科医生之间通常相似。关于 THA,在假体因素方面存在差异,低翻修率外科医生使用的假体种类较少,这些假体在 AOANJRR 中被认为具有高于预期的翻修率。低翻修率外科医生使用混合固定的比例较高,尽管骨水泥固定仍然是最常见的选择。在外科医生因素方面,低翻修率外科医生每年进行的 THA 手术超过 100 例,而其他外科医生每年进行的 THA 手术少于 50 例。一般来说,与每年进行的病例数量相比,外科医生(低翻修率外科医生和其他外科医生)之间的分组在手术经验方面差异较小,尽管低翻修率外科医生的平均手术经验年限更长,每年进行的病例数更多。关于 TKA,与 THA 相比,假体因素存在更多差异,低翻修率外科医生更频繁地进行髌骨表面置换,使用 AOANJRR 确定的最佳表现假体组合(翻修率最低),使用的假体在 AOANJRR 中被认为具有高于预期的翻修率,使用超高交联聚乙烯,以及使用更高比例的骨水泥固定与其他外科医生相比。在外科医生因素方面,低翻修率外科医生每年进行的 TKA 手术超过 100 例,而所有其他外科医生每年进行的 TKA 手术少于 50 例。同样,一般来说,与每年进行的病例数量相比,外科医生(低翻修率外科医生和其他外科医生)之间的分组在手术经验方面差异较小,尽管低翻修率外科医生的平均手术经验年限更长,每年进行的病例数更多。

结论

澳大利亚翻修率最低的 THA 和 TKA 手术显示出所有导致翻修的主要原因的减少,特别是与这些手术技术性能相关的翻修原因。THA 和 TKA 的低翻修率外科医生与所有其他外科医生的患者因素相似。低翻修率 THA 外科医生更有可能有选择地使用骨水泥固定。低翻修率 TKA 外科医生更有可能进行髌骨表面置换、交联聚乙烯和骨水泥固定。低翻修率 THA 和 TKA 外科医生更有可能使用 AOANJRR 确定的最佳表现假体组合,并使用 AOANJRR 确定的具有高于预期翻修率的假体数量较少。为了降低 THA 和 TKA 的翻修率,外科医生应考虑解决与假体选择相关的可修改因素。未来的研究应确定除了每年手术量之外,对改善假体存活率很重要的外科医生因素。

证据水平

III 级,治疗性研究。

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