Ladak Malika
Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1.
Can Vet J. 2020 May;61(5):534-536.
A 3-year-old spayed female Labrador retriever dog was presented with clinical signs of lethargy, vomiting, hyporexia, and increased respiratory effort. An exploratory laparotomy was conducted and a liver biopsy submitted for histopathologic evaluation revealed moderate multifocal coalescing pyogranulomatous hepatitis. Clinical signs, hematological parameters, and liver histopathology suggested an infectious etiology, such as leptospirosis, mycobacteriosis, or fungal infection. Polymerase chain reaction (PCR) and immunohistochemistry (IHC) for leptospirosis were negative. The infectious etiology was not identified, but leptospirosis may have played a role in the disease.
一只3岁已绝育的雌性拉布拉多寻回犬出现嗜睡、呕吐、食欲减退和呼吸费力等临床症状。进行了剖腹探查术，送检的肝活检组织经组织病理学评估显示为中度多灶性融合性脓性肉芽肿性肝炎。临床症状、血液学参数和肝脏组织病理学提示为感染性病因，如钩端螺旋体病、分枝杆菌病或真菌感染。钩端螺旋体病的聚合酶链反应（PCR）和免疫组织化学（IHC）检测结果均为阴性。虽然未确定感染性病因，但钩端螺旋体病可能在该疾病中起了一定作用。
