Sahu Kamal Kant, Mishra Ajay Kumar, Lal Amos
Department of Internal Medicine, Saint Vincent Hospital, Worcester, MA, USA.
Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN, USA.
Ann Transl Med. 2020 Mar;8(6):393. doi: 10.21037/atm.2020.02.92.
Recently, a new coronavirus disease (COVID-19) has emerged as a respiratory infection with significant concern for global public health hazards. With an initial suspicion of the animal to the human transmission for earlier cases, now the paradigm has shifted towards human to human transmission via droplets, contacts and/or through fomites. with each passing day, more and more confirmed cases are being reported worldwide which has alarmed the global authorities including World Health Organization (WHO), Centers for Disease Control and Prevention (CDC) and the National Health Commission of the People's Republic of China to take immediate action in order to reduce the transmission and subsequent mortalities associated with COVID-19 to as minimum as possible. Unfortunately, like the previous Coronavirus outbreaks, there is no definite antiviral therapy for the treatment of confirmed cases and hence preventing ourselves from contracting 2019-nCoV is the best way to prevent it from becoming pandemic. Herein, we aim to discuss the latest updates on the origin, genomic characteristics, diagnosis, treatment options and current efforts being made by international health organizations with regards to the 2019-nCoV outbreak.
最近，一种新型冠状病毒疾病（COVID-19）作为一种呼吸道感染出现，引起了全球对公共卫生危害的高度关注。早期病例最初怀疑是动物传人，现在模式已转向通过飞沫、接触和/或通过污染物进行人传人。随着时间的推移，全球报告的确诊病例越来越多，这已促使包括世界卫生组织（WHO）、疾病控制与预防中心（CDC）以及中华人民共和国国家卫生健康委员会在内的全球当局立即采取行动，以尽可能减少与COVID-19相关的传播及随后的死亡病例。不幸的是，与之前的冠状病毒爆发一样，对于确诊病例没有确切的抗病毒治疗方法，因此防止自己感染2019-nCoV是防止其成为大流行病的最佳方法。在此，我们旨在讨论关于2019-nCoV爆发的起源、基因组特征、诊断、治疗选择以及国际卫生组织目前所做努力的最新情况。
