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直肠乙状结肠深部浸润型子宫内膜异位症经节段切除术与间盘切除术治疗术后狭窄风险的比较:一项回顾性研究。

Risk of Postoperative Stenosis after Segmental Resection versus Disk Excision for Deep Endometriosis Infiltrating the Rectosigmoid: A Retrospective Study.

机构信息

Expert Center in the Diagnosis and Multidisciplinary Management of Endometriosis (Drs. Braund, Hennetier, Klapczynski, and Scattarelli).

Department of Surgery (Drs. Coget, Bridoux, and Tuech), Rouen University Hospital, Rouen.

出版信息

J Minim Invasive Gynecol. 2021 Jan;28(1):50-56. doi: 10.1016/j.jmig.2020.04.034. Epub 2020 Apr 30.

Abstract

STUDY OBJECTIVE

To assess the prevalence, risk factors, and management of bowel stenosis after surgery for deep infiltrating endometriosis of the rectosigmoid using either disk excision (DE) or segmental resection (SR).

DESIGN

Retrospective study using data from consecutive cases recorded in the North-West Inter Regional Female Cohort for Patients with Endometriosis database.

SETTING

University tertiary referral center.

PATIENTS

Four hundred thirty-one consecutive patients managed for rectosigmoid endometriosis were enrolled in our study.

INTERVENTIONS

Laparoscopic SR or DE.

MEASUREMENTS AND MAIN RESULTS

One hundred sixty-five patients underwent DE, and 266 patients underwent SR. Large nodules ≥3 cm in diameter were more frequent in the SR group (73.3% vs 66.1%), whereas nodules infiltrating the low rectum were 3 times more frequent in the DE group (35.9% vs 11.3%). The frequency of vaginal excision (67.9% vs 62%) and stoma (46.7% vs 44.4%) were comparable between the DE and SR groups. Twenty-three patients presented with postoperative colorectal stenosis after SR (8.6%) versus none after DE (p <.001). Treatment of colorectal stenosis involved dilatation in 20 (87%) cases and SR in 4 (17.4%) cases. For 1 patient, dilatation resulted in rectosigmoid injury requiring SR, followed by rectovaginal fistula. The logistic regression model identified a diverting stoma as the sole risk factor independently related to the risk of postoperative stenosis after SR.

CONCLUSION

Bowel stenosis after surgery for deep infiltrating endometriosis occurred in patients who underwent SR, most of them with a diverting stoma, whereas no cases of stenosis were reported in patients who underwent DE, with or without stoma.

摘要

研究目的

评估直肠乙状结肠深部浸润性子宫内膜异位症采用环形切除(DE)或节段切除(SR)术后肠狭窄的发生率、危险因素和处理方法。

研究设计

利用西北区域性女性子宫内膜异位症患者队列数据库中连续记录的病例数据进行回顾性研究。

研究地点

大学三级转诊中心。

研究对象

本研究共纳入 431 例直肠乙状结肠子宫内膜异位症患者。

干预措施

腹腔镜 SR 或 DE。

测量和主要结果

165 例行 DE,266 例行 SR。SR 组中直径≥3cm 的大结节更为常见(73.3%比 66.1%),而 DE 组中累及低位直肠的结节则多 3 倍(35.9%比 11.3%)。阴道切除(67.9%比 62%)和造口(46.7%比 44.4%)的频率在 DE 和 SR 两组间无差异。23 例 SR 术后出现结直肠狭窄(8.6%),而 DE 术后无 1 例(p<.001)。结直肠狭窄的治疗包括扩张 20 例(87%)和 SR 4 例(17.4%)。1 例患者因扩张导致直肠乙状结肠损伤,需行 SR 治疗,随后出现直肠阴道瘘。Logistic 回归模型确定预防性造口是与 SR 术后狭窄风险相关的唯一独立危险因素。

结论

在接受 SR 治疗的深部浸润性子宫内膜异位症患者中发生肠狭窄,其中大多数患者有预防性造口,而在接受 DE 治疗的患者中,无论是否有造口,均未发生狭窄。

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