Gu Huaxin, Wang Shixiu, Wang Xinghuo, Yu Xiang, Hu Menghong, Huang Wei, Wang Youji
State Key Laboratory of Satellite Ocean Environment Dynamics, Second Institute of Oceanography, Ministry of Natural Resources, Hangzhou 310012, China; International Research Center for Marine Biosciences, Shanghai Ocean University, Ministry of Science and Technology, China; Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, National Demonstration Center for Experimental Fisheries Science Education, Shanghai Ocean University, Shanghai, China; Key Laboratory of Marine Ecosystem and Biogeochemistry, State Oceanic Administration & Second Institute of Oceanography, Ministry of Natural Resources, Hangzhou 310012, China.
International Research Center for Marine Biosciences, Shanghai Ocean University, Ministry of Science and Technology, China.
J Hazard Mater. 2020 Oct 5;397:122773. doi: 10.1016/j.jhazmat.2020.122773. Epub 2020 Apr 25.
Microplastics (MPs) have become a severe concern in marine environment worldwide. Micro-polystyrene particles have been proved to accumulate in vivo and caused disorders of digestion, antioxidant system, immunity and intestinal microflora, but little is known about the effects of nano-polystyrene (nano-PS). In order to understand response mechanism of marine fish to nano-PS, the effects of nanoplastics on the intestinal health and growth performance of the juvenile Larimichthys crocea were investigated. After 14-d exposure, the reduced digestive enzyme activities indicated that nano-PS had a negative impact on the digestion and absorption of juvenile fish. Moreover, analysis of the intestinal microbiota showed that the proportion of the three-dominant bacterial phyla (Bacteroidetes, Proteobacteria and Firmicutes) in the gut changed significantly, accompanied by a significant increase of potentially pathogenic bacteria (Parabacteroides and Alistipes). In addition, lysozyme activity and specific growth rate (SGR) were significantly reduced, and total mortality of juvenile fish was significantly increased. Overall, nano-PS exposure was harmful for the health of juvenile fish, which might threaten their population in the long term.
微塑料已成为全球海洋环境中一个严重令人担忧的问题。微聚苯乙烯颗粒已被证明会在体内蓄积，并导致消化、抗氧化系统、免疫和肠道微生物群紊乱，但关于纳米聚苯乙烯（纳米PS）的影响却知之甚少。为了了解海水鱼类对纳米PS的反应机制，研究了纳米塑料对大黄鱼幼鱼肠道健康和生长性能的影响。经过14天的暴露，消化酶活性降低表明纳米PS对幼鱼的消化和吸收有负面影响。此外，肠道微生物群分析表明，肠道中三个优势细菌门（拟杆菌门、变形菌门和厚壁菌门）的比例发生了显著变化，同时潜在病原菌（副拟杆菌属和梭菌属）显著增加。此外，溶菌酶活性和特定生长率（SGR）显著降低，幼鱼的总死亡率显著增加。总体而言，暴露于纳米PS对幼鱼健康有害，从长远来看可能会威胁到它们的种群数量。
