移植受者中严重急性呼吸综合征冠状病毒2感染的推荐预防和管理策略。

Ju Chun-Rong, Lian Qiao-Yan, Zhang Jian-Heng, Qiu Tao, Cai Zhi-Tao, Jiang Wen-Yang, Zhang Jing, Cheng Qin, Chen Gang, Li Ning, Wang Chun-Yan, He Jian-Xing

State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510120, China.

Department of Kidney Transplantation, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, China.

Chronic Dis Transl Med. 2020 Mar 27;6(2):87-97. doi: 10.1016/j.cdtm.2020.02.003. eCollection 2020 Jun.

Since December 2019, increasing attention has been paid to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic in Wuhan, China. SARS-CoV-2 primarily invades the respiratory tract and lungs, leading to pneumonia and other systemic disorders. The effect of SARS-CoV-2 in transplant recipients has raised significant concerns, especially because there is a large population of transplant recipients in China. Based on the current epidemic situation, this study reviewed publications on this virus and coronavirus disease 2019 (COVID-19), analyzed common features of respiratory viral pneumonias, and presented the currently reported clinical characteristics of COVID-19 in transplant recipients to improve strategies regarding the diagnosis and treatment of COVID-19 in this special population.

自2019年12月以来，中国武汉的严重急性呼吸综合征冠状病毒2（SARS-CoV-2）疫情受到越来越多关注。SARS-CoV-2主要侵袭呼吸道和肺部，导致肺炎及其他全身性疾病。SARS-CoV-2对移植受者的影响引发了重大关注，特别是因为中国有大量移植受者。基于当前疫情形势，本研究回顾了关于该病毒和2019冠状病毒病（COVID-19）的出版物，分析了呼吸道病毒性肺炎的共同特征，并呈现了目前报道的移植受者中COVID-19的临床特征，以改进针对这一特殊人群的COVID-19诊断和治疗策略。