Shaikh Sana Saffiruddin, Jose Anooja P, Nerkar Disha Anil, Vijaykumar Kv Midhuna, Shaikh Saquib Khaleel
Y. B. Chavan College of Pharmacy, Dr. Rafiq Zakaria Campus, Aurangabad, 431001 India.
Government College of Pharmacy, Aurangabad, 431001 India.
Futur J Pharm Sci. 2020;6(1):116. doi: 10.1186/s43094-020-00133-y. Epub 2020 Nov 17.
Coronavirus (SARS-CoV-2), the cause of COVID-19, a fatal disease emerged from Wuhan, a large city in the Chinese province of Hubei in December 2019.
The World Health Organization declared COVID-19 as a pandemic due to its spread to other countries inside and outside Asia. Initial confirmation of the pandemic shows patient exposure to the Huanan seafood market. Bats might be a significant host for the spread of coronaviruses via an unknown intermediate host. The human-to-human transfer has become a significant concern due to one of the significant reasons that is asymptomatic carriers or silent spreaders. No data is obtained regarding prophylactic treatment for COVID-19, although many clinical trials are underway.
The most effective weapon is prevention and precaution to avoid the spread of the pandemic. In this current review, we outline pathogenesis, diagnosis, treatment, ongoing clinical trials, prevention, and precautions. We have also highlighted the impact of pandemic worldwide and challenges that can help to overcome the fatal disease in the future.
冠状病毒(严重急性呼吸综合征冠状病毒2)是2019年12月在中国湖北省大城市武汉出现的致命疾病新冠肺炎的病原体。
世界卫生组织宣布新冠肺炎为大流行病,因其已传播到亚洲内外的其他国家。该大流行病的初步确认显示患者接触过华南海鲜市场。蝙蝠可能是冠状病毒通过未知中间宿主传播的重要宿主。由于无症状携带者或隐性传播者这一重要原因,人际传播已成为一个重大问题。尽管许多临床试验正在进行,但尚未获得关于新冠肺炎预防性治疗的数据。
最有效的武器是预防和防范,以避免大流行病的传播。在本次综述中,我们概述了发病机制、诊断、治疗、正在进行的临床试验、预防和防范措施。我们还强调了该大流行病在全球范围内的影响以及有助于未来战胜这种致命疾病的挑战。