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电刺激下磁声声源远场测量方法的初步体内研究

A preliminary in vivo study of a method for measuring magneto-acoustic sonic source under electrical stimulation.

出版信息

Technol Health Care. 2020;28(S1):421-432. doi: 10.3233/THC-209043.

DOI:10.3233/THC-209043
PMID:32364175
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7369092/
Abstract

BACKGROUND

Stimulating current distribution in the tissue is unknown due to the complex distribution.

OBJECTIVE

A preliminary in vivo measurement of the magneto-acoustic (MA) signal of the human finger is performed in this study. The approach for locating the magneto-acoustic source of the stimulating current is studied.

METHODS

We use a lock-in amplifier to measure the MA signal under continuous wave electrical stimulation. The phase of the MA signal is used to extract the location of the sonic source. The experimental system is designed to measure the MA signal under electrical stimulation.

RESULTS

Preliminary experiments results show that the amplitude precision is improved to less than 1 μPa. The sonic source is located with millimetre precision.

CONCLUSIONS

We propose a new MA source-locating method with high measurement and location precision. This method will be significant to the study of the imaging and monitoring of the current distribution of electrical stimulation with high precision.

摘要

背景

由于刺激电流在组织中的分布复杂，其分布情况尚不清楚。

目的

本研究初步对人体手指的磁声（MA）信号进行了体内测量。研究了用于定位刺激电流磁声源的方法。

方法

我们使用锁相放大器在连续波电刺激下测量 MA 信号。MA 信号的相位用于提取声波源的位置。设计了实验系统来测量电刺激下的 MA 信号。

结果

初步实验结果表明，幅度精度提高到小于 1 μPa。声源远定位精度达到毫米级。

结论

我们提出了一种具有高精度测量和定位精度的新的 MA 源定位方法。该方法对于高精度电刺激电流分布的成像和监测研究具有重要意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4963/7369092/70b0054a6c84/thc-28-thc209043-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4963/7369092/2211af247e53/thc-28-thc209043-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4963/7369092/327b279d2163/thc-28-thc209043-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4963/7369092/66bc8fde76f0/thc-28-thc209043-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4963/7369092/b775387a0949/thc-28-thc209043-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4963/7369092/9c203cd629ae/thc-28-thc209043-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4963/7369092/d63baa756ec8/thc-28-thc209043-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4963/7369092/02f9a2f2392e/thc-28-thc209043-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4963/7369092/5a428fd9c3fa/thc-28-thc209043-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4963/7369092/70b0054a6c84/thc-28-thc209043-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4963/7369092/2211af247e53/thc-28-thc209043-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4963/7369092/327b279d2163/thc-28-thc209043-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4963/7369092/66bc8fde76f0/thc-28-thc209043-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4963/7369092/b775387a0949/thc-28-thc209043-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4963/7369092/9c203cd629ae/thc-28-thc209043-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4963/7369092/d63baa756ec8/thc-28-thc209043-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4963/7369092/02f9a2f2392e/thc-28-thc209043-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4963/7369092/5a428fd9c3fa/thc-28-thc209043-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4963/7369092/70b0054a6c84/thc-28-thc209043-g009.jpg

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本文引用的文献

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Sci Rep. 2018 Aug 30;8(1):13067. doi: 10.1038/s41598-018-31247-2.
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A Randomized Controlled Study: Effectiveness of Functional Electrical Stimulation on Wrist and Finger Flexor Spasticity in Hemiplegia.一项随机对照研究：功能性电刺激对偏瘫患者手腕和手指屈肌痉挛的疗效
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Ability of electrical stimulation therapy to improve the effectiveness of robotic training for paretic upper limbs in patients with stroke.
电刺激疗法提高中风患者瘫痪上肢机器人训练效果的能力。
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Magneto-acoustic imaging by continuous-wave excitation.连续波激发的磁声成像。
Med Biol Eng Comput. 2017 Apr;55(4):595-607. doi: 10.1007/s11517-016-1538-1. Epub 2016 Jul 1.
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Ultrahigh Frequency (100 MHz-300 MHz) Ultrasonic Transducers for Optical Resolution Medical Imagining.用于光学分辨率医学成像的超高频（100MHz-300MHz）超声换能器。
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