专题：“肝纤维化发病机制的细胞和分子机制”

Special Issue on "Cellular and Molecular Mechanisms Underlying the Pathogenesis of Hepatic Fibrosis".

机构信息

Institute of Molecular Pathobiochemistry, Experimental Gene Therapy and Clinical Chemistry (IFMPEGKC), RWTH University Hospital Aachen, D-52074 Aachen, Germany.

出版信息

Cells. 2020 Apr 29;9(5):1105. doi: 10.3390/cells9051105.

DOI:10.3390/cells9051105

PMID:32365575

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7291324/

Abstract

This Special issue contains 48 contributions highlighting novel findings and current concepts in basic and clinical liver fibrosis research. These articles emphasize issues on pathogenesis, cellular mediators, modulators, molecular pathways, disease-specific therapies, scoring systems, as well as novel preclinical animal models for the study of liver fibrogenesis. This editorial aims to briefly summarize the content of these papers.

摘要

本期特刊包含 48 篇文章，重点介绍了基础和临床肝纤维化研究中的新发现和当前概念。这些文章强调了发病机制、细胞介质、调节剂、分子途径、针对特定疾病的治疗方法、评分系统以及用于研究肝纤维化的新型临床前动物模型等问题。本社论旨在简要总结这些论文的内容。