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性别多样化儿童和青少年的心理社会挑战和激素治疗。叙事性综述。

Psychosocial challenges and hormonal treatment in gender diverse children and adolescents. A narrative review.

机构信息

General Psychiatry Department, Sint-Lucas, Bruges, Belgium, Ghent University, Ghent, Belgium.

Dept Child & Adolescent psychiatry, Center for Gender and Sexuology, Pediatric Gender Clinic, Ghent University Hospital, Ghent, Belgium.

出版信息

Int J Impot Res. 2021 Mar;33(2):217-227. doi: 10.1038/s41443-020-0291-z. Epub 2020 May 4.

DOI:10.1038/s41443-020-0291-z
PMID:32366985
Abstract

Gender dysphoria (GD) in children and adolescents is a condition that is characterized by an incongruence between the assigned and experienced gender. Despite the diversity in clinical presentation, literature demonstrates that GD might lead to poor mental health and high rates of co-occurring psychopathology. Due to the overlap of physical aspects as well as psychological needs in these children, a multidisciplinary approach is highly desirable. The aim of this narrative review is to give an overview of recent literature on several topics relevant in this domain. Guidelines on psychological counseling and hormonal treatment are given and challenging topics subject to controversy are explained. Furthermore, attention is drawn to the risks and protective factors in psychological functioning, including the growing evidence of a frequent co-occurrence with Autism Spectrum Disorder. Finally the psycho-sexual development in these children, the impact on fertility and fertility preservation are discussed.

摘要

儿童和青少年的性别焦虑症(GD)是一种表现为分配性别和体验性别之间不一致的病症。尽管临床表现存在多样性,但文献表明,GD 可能导致心理健康状况不佳和同时存在较高的精神病理学发生率。由于这些儿童在身体方面和心理需求方面存在重叠,因此非常需要采用多学科方法。本叙述性综述的目的是概述与该领域相关的几个主题的最新文献。提供了关于心理辅导和激素治疗的指南,并解释了存在争议的具有挑战性的主题。此外,还关注了心理功能方面的风险和保护因素,包括越来越多的证据表明其与自闭症谱系障碍经常同时发生。最后,讨论了这些儿童的性心理发展、对生育能力的影响和生育力保存。

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本文引用的文献

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Health considerations for transgender women and remaining unknowns: a narrative review.跨性别女性的健康考量及未知因素:一项叙述性综述
Ther Adv Endocrinol Metab. 2019 Aug 30;10:2042018819871166. doi: 10.1177/2042018819871166. eCollection 2019.
2
Texture profile analysis reveals a stiffer ovarian cortex after testosterone therapy: a pilot study.纹理分析显示睾酮治疗后卵巢皮质变硬:一项初步研究。
J Assist Reprod Genet. 2019 Sep;36(9):1837-1843. doi: 10.1007/s10815-019-01513-x. Epub 2019 Jul 20.
3
Self-perception of transgender clinic referred gender diverse children and adolescents.
儿科医生在儿童和青少年性别焦虑症管理中的作用。
Ital J Pediatr. 2023 Jun 14;49(1):71. doi: 10.1186/s13052-023-01466-z.
转诊至跨性别诊所的性别多样化儿童和青少年的自我认知。
Clin Child Psychol Psychiatry. 2019 Apr;24(2):388-401. doi: 10.1177/1359104518825279. Epub 2019 Jan 23.
4
Effects of Gender-Affirming Hormones on Lipid, Metabolic, and Cardiac Surrogate Blood Markers in Transgender Persons.跨性别者的性别肯定激素对血脂、代谢和心脏替代血液标志物的影响。
Clin Chem. 2019 Jan;65(1):119-134. doi: 10.1373/clinchem.2018.288241.
5
Gender Variance and the Autism Spectrum: An Examination of Children Ages 6-12 Years.性别差异与自闭症谱系:对 6-12 岁儿童的研究。
J Autism Dev Disord. 2019 Apr;49(4):1570-1585. doi: 10.1007/s10803-018-3843-z.
6
Revisiting the Link: Evidence of the Rates of Autism in Studies of Gender Diverse Individuals.重新审视关联:性别多样化个体研究中自闭症发病率的证据。
J Am Acad Child Adolesc Psychiatry. 2018 Nov;57(11):885-887. doi: 10.1016/j.jaac.2018.04.023.
7
Is There a Link Between Gender Dysphoria and Autism Spectrum Disorder?性别焦虑与自闭症谱系障碍之间是否存在关联?
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Evidence for a Change in the Sex Ratio of Children Referred for Gender Dysphoria: Data From the Gender Identity Development Service in London (2000-2017).伦敦性别认同发展服务处(2000-2017 年)转介性别焦虑儿童的性别比例变化证据。
J Sex Med. 2018 Oct;15(10):1381-1383. doi: 10.1016/j.jsxm.2018.08.002. Epub 2018 Sep 5.
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