Santos Tamara Fonseca Bastos, Dos Santos Carvalho Cleoni, de Almeida Mônica Aparecida, Delforno Tiago Palladino, Duarte Iolanda Cristina Silveira
Laboratory of Environmental Microbiology, Department of Biology, Federal University of São Carlos, Rodovia João Leme dos Santos Km 110, Sorocaba, SP 18052-780 Brazil.
3 Biotech. 2020 May;10(5):223. doi: 10.1007/s13205-020-02211-7. Epub 2020 Apr 30.
In this study, 19 endophytic fungi were isolated from and Seventeen strains were molecularly identified as belonging to the genera , and . Assays for detecting antioxidant activity were performed by free radical scavenging activity using the DDPH and ABTS + methods. Based on the results with DPPH, two strains were selected to evaluate the presence of flavonoids and anti-inflammatory activity. A strong positive correlation was found between these activities and the presence of flavonoids. The anti-inflammatory activity of endophytic fungi is under explored; however, the obtained the best result of 87.33% protection of erythrocytes and of 60.71%. This study demonstrated that endophytic fungi associated with selected plants are potential sources of novel antioxidant products.
在本研究中，从[具体植物名称]中分离出19种内生真菌。17个菌株经分子鉴定属于[具体属名1]和[具体属名2]属。采用DPPH和ABTS+法通过自由基清除活性进行抗氧化活性检测。基于DPPH的结果，选择两个菌株评估黄酮类化合物的存在及抗炎活性。发现这些活性与黄酮类化合物的存在之间存在强正相关。内生真菌的抗炎活性正在探索中；然而，[具体菌株名称]获得了最佳结果，红细胞保护率为87.33%，[具体指标2]为60.71%。本研究表明，与所选植物相关的内生真菌是新型抗氧化产品的潜在来源。
