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一种抗氧化剂诱导衰老的拟态蚤蝇(双翅目)过氧化物酶活性发生改变。

An antioxidant induced alterations in peroxidase activity in ageing Zaprionus paravittiger (Diptera).

作者信息

Wadhwa R, Kaur M, Sharma S P

机构信息

DNA Lab, Department of Human Genetics, Newcastle upon Tyne, U.K.

出版信息

Mech Ageing Dev. 1988 Nov 30;45(3):277-83. doi: 10.1016/0047-6374(88)90008-5.

Abstract

Sodium hypophosphite (1 x 10(3) microM) supplementation in the diet of Zaprionus paravittiger resulted in adaptive responses in the quantitative as well as qualitative activity of peroxidase. The changes in peroxidase were in compliance with the earlier reported sodium hypophosphite (SHP)-induced prolonged life span of flies (Wadhwa, R., Arch. Gerontol. Geriatr., 6 (1987) 141-147) and support the concept that antioxidative enzymes may serve as important longevity determinants.

摘要

在副带蚤蝇的饮食中补充次磷酸钠(1×10³微摩尔)会导致过氧化物酶在定量和定性活性方面产生适应性反应。过氧化物酶的变化与先前报道的次磷酸钠(SHP)诱导果蝇寿命延长的结果一致(Wadhwa,R.,《老年学与老年医学文献》,6(1987)141 - 147),并支持抗氧化酶可能是重要的寿命决定因素这一概念。

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