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用次磷酸钠喂养拟带蚤蝇的寿命研究。

Life span studies in Zaprionus paravittiger with sodium hypophosphite feeding.

作者信息

Wadhwa R, Rai N, Sharma S P

出版信息

Gerontology. 1986;32(3):141-7. doi: 10.1159/000212780.

Abstract

The median and maximum life spans of Zaprionus paravittiger at 26 +/- 2 degrees C were 35.45 +/- 0.39 and 70.0 +/- 1.00 days, respectively, in males and 39.93 +/- 0.40 and 77.67 +/- 0.58 days in females. Feeding of an antioxidant-sodium hypophoshite (SHP), 1, 10 1 X 10(2) and 1 X 10(3) microM-resulted in increased survival of both sexes. Further increase in SHP concentration accelerated the mortality rate. Secondly, the lipid peroxide level as measured by malondialdehyde content showed an age-related increase in normal as well as SHP-fed cohorts. However, the rate of increase was much slower in the latter. It is suggested that SHP, by virtue of its free-radical scavenging property, prolongs the life span of Z. paravittiger.

摘要

在26±2摄氏度条件下,拟带足蝇雄性的中位寿命和最大寿命分别为35.45±0.39天和70.0±1.00天,雌性分别为39.93±0.40天和77.67±0.58天。喂食抗氧化剂次磷酸钠(SHP),浓度分别为1、10、1×10²和1×10³微摩尔,导致两性的存活率均有所提高。SHP浓度进一步增加会加速死亡率。其次,通过丙二醛含量测定的脂质过氧化物水平显示,在正常以及喂食SHP的群体中,其随年龄增长而增加。然而,后者的增加速率要慢得多。有人提出,SHP凭借其自由基清除特性,延长了拟带足蝇的寿命。

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