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蛋氨酸诱导的衰老拟巴西果蝇(双翅目)寿命、抗氧化酶和过氧化物水平的变化

Methionine-induced alterations in the life span, antioxidant enzymes, and peroxide levels in aging Zaprionus paravittiger (Diptera).

作者信息

Sharma S P, Sharma M, Kakkar R

机构信息

Department of Zoology, Guru Nanak Dev University, Amritsar, India.

出版信息

Gerontology. 1995;41(2):86-93. doi: 10.1159/000213668.

Abstract

The median and maximum life spans of both sexes of Zaprionus paravittiger increased with methionine (100 mM) feeding. It was accompanied by higher catalase and peroxidase enzyme activities. The lipid peroxide level as measured by malondialdehyde content and the inorganic peroxides showed an increase with age and a decrease in methionine-fed insects. The reduction was, however, more pronounced in females than in males. The findings indicate that a life-prolonging effect of methionine on Z. paravittiger may be by virtue of its free radical scavenging effect.

摘要

用100 mM蛋氨酸喂养后,双带拟果蝇两性的平均寿命和最大寿命均有所增加。同时,过氧化氢酶和过氧化物酶的活性也更高。通过丙二醛含量测定的脂质过氧化物水平和无机过氧化物显示,随着年龄增长而增加,而在喂食蛋氨酸的昆虫中则有所下降。然而,这种下降在雌性中比在雄性中更为明显。研究结果表明,蛋氨酸对双带拟果蝇的寿命延长作用可能是由于其自由基清除作用。

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