Borkowski Dominik, Krucińska Izabella, Draczyński Zbigniew
Institute of Textile Materials and Polymer Composites, Lodz University of Technology, Żeromskiego 116, 90-924 Lodz, Poland.
Lukasiewicz Research Network - Institute of Biopolymers and Chemical Fibers, Skłodowskiej-Curie 19/27, 90-570 Lodz, Poland.
Polymers (Basel). 2020 May 2;12(5):1040. doi: 10.3390/polym12051040.
Active dressings based on natural polymers are becoming increasingly popular on the market. One of such polymers is alginate, which is characterized by biodegradability, resorbability, has no carcinogenic properties, does not have allergenic or hemostatic properties, and has a confirmed lack of toxicity. However, this polymer does not show biocidal and biostatic properties, therefore the purpose of this research was to select the appropriate conditions for the production of calcium alginate fibers modified with nano titanium dioxide and nano zinc oxide. It was assumed that the presence of nano metal oxide fillers will give antibacterial properties to formed fibers, which were used to form nonwovens. The following article presents a comparative analysis of nonwovens made of alginate fibers, without nano additives, with nonwovens made of alginate fibers containing in their structure 7% titanium dioxide and nonwovens made of alginate fibers containing 2% ZnO. The selection of the nano additive content was determined by the spinning ability of the developed polymer solutions. Based on the results contained in the article, it was found that the introduction of modifiers in the structure of fibers increases the diameter of the fiber pores, which improves the sorption and retention properties of the obtained fibers, and also gives differentiated antibacterial properties to the obtained nonwovens depending on the type of nano additive used. Greater activity against Escherichia coli, Staphylococcus aureus strains and Aspergillus Niger molds was shown in nonwovens made of 2% ZnO modified fibers compared to nonwovens made from TiO modified fibers.
基于天然聚合物的活性敷料在市场上越来越受欢迎。藻酸盐就是这类聚合物之一，其特点是具有生物可降解性、可吸收性，无致癌性，无致敏或止血特性，且已证实无毒性。然而，这种聚合物不具备杀菌和抑菌特性，因此本研究的目的是选择合适的条件来生产用纳米二氧化钛和纳米氧化锌改性的海藻酸钙纤维。假定纳米金属氧化物填料的存在将赋予所形成纤维抗菌性能，这些纤维用于制成无纺布。以下文章对由不含纳米添加剂的藻酸盐纤维制成的无纺布、由结构中含有7%二氧化钛的藻酸盐纤维制成的无纺布以及由含有2%氧化锌的藻酸盐纤维制成的无纺布进行了对比分析。纳米添加剂含量的选择取决于所开发聚合物溶液的纺丝能力。根据文章中的结果发现，在纤维结构中引入改性剂会增加纤维孔隙的直径，这改善了所得纤维的吸附和保留性能，并且根据所使用的纳米添加剂类型，还会赋予所得无纺布不同的抗菌性能。与由二氧化钛改性纤维制成的无纺布相比，由2%氧化锌改性纤维制成的无纺布对大肠杆菌、金黄色葡萄球菌菌株和黑曲霉霉菌表现出更大的活性。
