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结构骨的激光制造:表面形态和生物矿化评估。

Laser fabrication of structural bone: surface morphology and biomineralization assessment.

作者信息

Banerjee Sucharita, Pantawane Mangesh V, Dahotre Narendra B

机构信息

Laboratory for Laser Aided Additive and Subtractive Manufacturing, Virtual Center for Advanced Orthopedics, Department of Materials Science and Engineering, University of North Texas, 1155 Union Circle-305310, Denton, TX, 76203-5017, USA.

出版信息

Lasers Med Sci. 2021 Feb;36(1):131-137. doi: 10.1007/s10103-020-03023-0. Epub 2020 May 6.

DOI:10.1007/s10103-020-03023-0
PMID:32372236
Abstract

The current work explores the surface morphology of the laser-ablated bone using Yb-fiber coupled Nd:YAG laser (λ = 1064 nm) in continuous wave mode. As the laser-ablated region contains physiochemically modified carbonized and nonstructural region, it becomes unknown material for the body. Thus, biomineralization on such a laser-ablated region was assessed by in vitro immersion test in noncellular simulated body fluid. The presence of hydroxyapatite was detected in the precipitated mineral product using scanning electron microscopy equipped with energy dispersive spectroscopy, and X-ray diffraction analysis. The effect of varying laser parameters on distribution of surface morphology features was identified and its corresponding effect on biomineralization was studied.

摘要

当前工作研究了在连续波模式下使用镱光纤耦合钕

钇铝石榴石激光(λ = 1064 nm)对骨进行激光消融后的表面形态。由于激光消融区域包含物理化学性质改变的碳化和非结构区域,它对身体而言成为未知物质。因此,通过在无细胞模拟体液中进行体外浸泡试验来评估在这种激光消融区域上的生物矿化作用。使用配备能量色散光谱的扫描电子显微镜和X射线衍射分析,在沉淀的矿物产物中检测到了羟基磷灰石的存在。确定了不同激光参数对表面形态特征分布的影响,并研究了其对生物矿化的相应影响。

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2
A review of the physiological and histological effects of laser osteotomy.激光截骨术的生理和组织学效应综述。
J Med Eng Technol. 2017 Jan;41(1):1-12. doi: 10.1080/03091902.2016.1199743. Epub 2016 Jun 27.
3
A comparative investigation of bone surface after cutting with mechanical tools and Er:YAG laser.
使用机械工具和铒钇铝石榴石激光切割后骨表面的对比研究。
Lasers Surg Med. 2015 Jul;47(5):426-32. doi: 10.1002/lsm.22352. Epub 2015 May 6.
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Advances in bone surgery: the Er:YAG laser in oral surgery and implant dentistry.骨外科进展:铒激光在口腔外科及种植牙科中的应用
Clin Cosmet Investig Dent. 2010 Jun 30;2:47-62. Print 2010.
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Femtosecond laser ablation of bovine cortical bone.飞秒激光烧蚀牛颅骨。
J Biomed Opt. 2012 Dec;17(12):125005. doi: 10.1117/1.JBO.17.12.125005.
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Biofabrication. 2010 Jun;2(2):025001. doi: 10.1088/1758-5082/2/2/025001. Epub 2010 Mar 10.
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