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Drug repurposing in the era of COVID-19: a call for leadership and government investment.

作者信息

Martin Jennifer H, Bowden Nikola A

机构信息

University of Newcastle, Newcastle, NSW.

Hunter New England Health, Newcastle, NSW.

出版信息

Med J Aust. 2020 Jun;212(10):450-452.e1. doi: 10.5694/mja2.50603. Epub 2020 May 6.

DOI:10.5694/mja2.50603
PMID:32372435
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7267456/
Abstract
摘要

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N Engl J Med. 2020 Jun 11;382(24):2327-2336. doi: 10.1056/NEJMoa2007016. Epub 2020 Apr 10.
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Coronavirus puts drug repurposing on the fast track.冠状病毒使药物重新利用走上快车道。
Nat Biotechnol. 2020 Apr;38(4):379-381. doi: 10.1038/d41587-020-00003-1.
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Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial.羟氯喹和阿奇霉素治疗 COVID-19：一项开放标签非随机临床试验的结果。
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Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2.基于网络的2019新型冠状病毒（2019-nCoV/SARS-CoV-2）药物重新利用研究
Cell Discov. 2020 Mar 16;6:14. doi: 10.1038/s41421-020-0153-3. eCollection 2020.
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A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19.洛匹那韦-利托那韦治疗成人重症 COVID-19 患者的临床试验。
N Engl J Med. 2020 May 7;382(19):1787-1799. doi: 10.1056/NEJMoa2001282. Epub 2020 Mar 18.
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Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?高血压和糖尿病患者感染新型冠状病毒肺炎（COVID-19）的风险会增加吗？
Lancet Respir Med. 2020 Apr;8(4):e21. doi: 10.1016/S2213-2600(20)30116-8. Epub 2020 Mar 11.
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Evidence for angiotensin-converting enzyme 2 as a therapeutic target for the prevention of pulmonary hypertension.血管紧张素转换酶2作为预防肺动脉高压治疗靶点的证据。
Am J Respir Crit Care Med. 2009 Jun 1;179(11):1048-54. doi: 10.1164/rccm.200811-1678OC. Epub 2009 Feb 26.
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Drug repositioning: identifying and developing new uses for existing drugs.药物重新定位：识别并开发现有药物的新用途。
Nat Rev Drug Discov. 2004 Aug;3(8):673-83. doi: 10.1038/nrd1468.
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Erectile-dysfunction therapies.勃起功能障碍治疗方法
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