Simonsen Claus Z, Speiser Lasse, Hansen Ib Tønder, Jayne David, von Weitzel-Mudersbach Paul
Department of Neurology, Aarhus University Hospital, Aarhus, Denmark.
Department of Neuroradiology, Aarhus University Hospital, Aarhus, Denmark.
Front Neurol. 2020 Apr 16;11:287. doi: 10.3389/fneur.2020.00287. eCollection 2020.
Giant cell arteritis (GCA) is the most common primary systemic vasculitis predominantly affecting large and medium sized vessels. In rare cases, the vasculitis can affect the vessels of the brain. We describe four cases of GCA with involvement of the cerebral vessels causing stroke. These cases were unresponsive to aggressive immunosuppression and we opted to treat with endovascular balloon dilatation of the stenotic areas. The procedure was safe. The four patients were treated in nine sessions and a total of 16 vessels were treated. We observed two dissections with no clinical influence on the patients. In patients with stroke due to progressive GCA that is non-responsive to immunosuppression, endovascular therapy is feasible.
巨细胞动脉炎(GCA)是最常见的主要累及大中型血管的原发性系统性血管炎。在罕见情况下,血管炎可累及脑血管。我们描述了4例累及脑血管导致中风的GCA病例。这些病例对积极的免疫抑制治疗无反应,因此我们选择对狭窄区域进行血管内球囊扩张治疗。该操作是安全的。这4例患者共接受了9次治疗,共治疗了16根血管。我们观察到2例血管夹层,对患者无临床影响。对于因进行性GCA导致的中风且对免疫抑制治疗无反应的患者,血管内治疗是可行的。