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频繁洗手预防新冠病毒可能导致手部皮炎:应对小贴士

Frequent Hand Washing for COVID-19 Prevention Can Cause Hand Dermatitis: Management Tips.

作者信息

Beiu Cristina, Mihai Mara, Popa Liliana, Cima Luiza, Popescu Marius N

机构信息

Oncologic Dermatology, Elias Emergency University Hospital, "Carol Davila" University of Medicine and Pharmacy, Bucharest, ROU.

Pharmacy, "Carol Davila" University of Medicine and Pharmacy, Bucharest, ROU.

出版信息

Cureus. 2020 Apr 2;12(4):e7506. doi: 10.7759/cureus.7506.

Abstract

Coronavirus disease 2019 (COVID-19) continues to spread globally, outpacing the capacity and resources of health systems worldwide. A therapeutic vaccine is not yet on the rise, and preventive measures are the current approach to restraint the transmission of cases. As the virus is highly contagious via respiratory route (droplets from infected persons, widely spread by coughing or sneezing) and via contact with contaminated surfaces, community transmission and spread can be decreased through the practice of regular and diligent hand hygiene. Frequent hand washing implies a prolonged exposure to water and other chemical or physical agents and may induce several pathophysiologic changes, such as epidermal barrier disruption, impairment of keratinocytes, the subsequent release of proinflammatory cytokines, activation of the skin immune system, and delayed-type hypersensitivity reactions. Adverse dermatologic effects, such as excessive skin dryness or even contact dermatitis (particularly the irritant subtype and, to a lesser extent, the allergic subtype), can occur, especially in individuals with a history of atopic dermatitis. These skin conditions are perfectly manageable, and applying a moisturizer immediately after washing hands or after using a portable hand sanitizer is the cornerstone in preventing the development of eczematous changes in the hands. In the current global context, the potential occurrence of these dermatological adverse events should in no way cause people to deviate from strict hand hygiene rules.

摘要

2019冠状病毒病(COVID-19)在全球持续蔓延,超出了全球卫生系统的应对能力和资源。治疗性疫苗尚未出现,目前控制病例传播的方法是采取预防措施。由于该病毒通过呼吸道途径(感染者咳嗽或打喷嚏产生的飞沫)以及接触受污染表面具有高度传染性,因此通过经常、认真地洗手可以减少社区传播和扩散。频繁洗手意味着长时间接触水和其他化学或物理制剂,可能会引发多种病理生理变化,如表皮屏障破坏、角质形成细胞受损、随后促炎细胞因子的释放、皮肤免疫系统激活以及迟发型超敏反应。可能会出现不良皮肤影响,如皮肤过度干燥甚至接触性皮炎(尤其是刺激性亚型,在较小程度上还有过敏性亚型),特别是有特应性皮炎病史的个体。这些皮肤状况完全可以控制,洗手后或使用便携式洗手液后立即涂抹保湿霜是预防手部湿疹样变化的关键。在当前全球背景下,这些皮肤不良事件潜在的发生绝不应该导致人们偏离严格的手部卫生规则。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee91/7195203/bc523665e83b/cureus-0012-00000007506-i01.jpg

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