Department of Chemistry, University College London, London, WC1H 0AJ, UK.
Tianjin Key Laboratory of Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, 300072, P. R. China.
Soft Matter. 2020 May 21;16(19):4569-4573. doi: 10.1039/d0sm00306a.
The simple and scalable synthesis of poly[2-(methacryloyloxy)ethyl phosphorylcholine] (PMPC)-coated conducting polymer (CP) nanocomposites is described. These functional nanocomposites exhibit tunable absorption in the near-infrared region with relatively high photothermal efficiencies. More importantly, their potential for bio-imaging and therapeutic treatment is proven by cellular uptake and cytotoxicity studies.
聚2-(甲基丙烯酰氧)乙基磷酸胆碱-包覆的导电聚合物(CP)纳米复合材料的简单、可扩展的合成方法被描述。这些功能纳米复合材料在近红外区域具有可调的吸收,具有相对较高的光热效率。更重要的是,通过细胞摄取和细胞毒性研究证明了它们在生物成像和治疗方面的潜力。