Department of Paediatrics, University of Oxford, Oxford, United Kingdom.
Department of Primary Care and Public Health, School of Public Health, Imperial College London, London, United Kingdom.
J Am Med Inform Assoc. 2020 Jun 1;27(6):976-980. doi: 10.1093/jamia/ocaa036.
The use of real-world evidence for health care research and evaluation is growing. Mobile health apps have often-overlooked potential to contribute valuable real-world data that are not captured by other sources and could provide data that are more cost-effective and generalizable than can randomized controlled trials. However, there are several challenges that must be overcome to realize the potential value of patient-used mobile health app real-world data, including data quality, motivation for long-term use, privacy and security, methods of analysis, and standardization and integration. Addressing these challenges will increase the value of data from mobile health apps to inform real-world evidence and improve patient empowerment, clinical management, disease research, and treatment development.
真实世界证据在医疗保健研究和评估中的应用正在不断增加。移动医疗应用程序常常被忽视，它们有可能提供其他来源无法捕捉到的有价值的真实世界数据，并且可以提供比随机对照试验更具成本效益和更具普遍性的数据。然而，要实现患者使用的移动医疗应用程序真实世界数据的潜在价值，还必须克服几个挑战，包括数据质量、长期使用的动机、隐私和安全、分析方法以及标准化和集成。解决这些挑战将提高移动医疗应用程序数据的价值，为真实世界证据提供信息，并增强患者的自主权、临床管理、疾病研究和治疗开发。
