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较高水平的酒精使用与人类免疫缺陷病毒感染者的潜伏性结核病感染相关。

Higher Levels of Alcohol Use Are Associated With Latent Tuberculosis Infection in Adults Living With Human Immunodeficiency Virus.

机构信息

Division of HIV, Infectious Diseases and Global Medicine, University of California San Francisco, San Francisco, California, USA.

Center for AIDS Prevention Studies, University of California San Francisco, San Francisco, California, USA.

出版信息

Clin Infect Dis. 2021 Mar 1;72(5):865-868. doi: 10.1093/cid/ciaa527.

Abstract

We assessed associations between hazardous alcohol use and latent tuberculosis infection (LTBI) among adults living with human immunodeficiency virus (HIV) in Uganda. We compared tuberculin skin test positivity across medium, high, and very-high alcohol use levels, classified by AUDIT-C scores. In multivariable analysis, very high use was associated with LTBI (adjusted odds ratio 1.61, 95% confidence interval: 1.03-2.50).

摘要

我们评估了在乌干达艾滋病毒(HIV)感染者中,危险饮酒与潜伏性结核感染(LTBI)之间的关联。我们比较了按 AUDIT-C 评分分类的中等、高和极高饮酒水平的结核菌素皮肤试验阳性率。在多变量分析中,非常高的饮酒量与 LTBI 相关(校正比值比 1.61,95%置信区间:1.03-2.50)。

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