Johns Hopkins University Bloomberg School of Public Health , Baltimore, Maryland.
Perinatal HIV Research Unit , University of Witwatersrand , Johannesburg , South Africa ; Johns Hopkins University Center for Tuberculosis Research , Baltimore, Maryland.
Open Forum Infect Dis. 2015 Jan 20;2(1):ofu120. doi: 10.1093/ofid/ofu120. eCollection 2015 Jan.
Tuberculosis is the leading cause of death among adults infected with human immunodeficiency virus (HIV), and rates of tuberculosis remain high even after preventive therapy. Among 908 HIV-infected adults in a trial of preventive treatment, we found self-reported alcohol consumption, low baseline CD4 count, high baseline viral load, and tuberculin skin test size >15 mm as independent risk factors for incident tuberculosis.
结核病是感染人类免疫缺陷病毒 (HIV) 的成年人的主要死因，即使在预防性治疗之后，结核病的发病率仍然很高。在一项预防性治疗试验中，我们对 908 名感染 HIV 的成年人进行了研究，发现自我报告的饮酒、低基线 CD4 计数、高基线病毒载量以及结核菌素皮肤试验大小 >15 毫米是结核病发病的独立危险因素。
