Field D J, Smith H, Mason E, Milner A D
Department of Child Health, University of Leicester, UK.
Paediatr Perinat Epidemiol. 1988 Jul;2(3):213-9. doi: 10.1111/j.1365-3016.1988.tb00209.x.
The increasing influence of very immature infants on perinatal mortality rates (PMR) led us to question the usefulness of this parameter in assessing perinatal care. To examine this further we have compared the incidence of perinatal asphyxia amongst mature babies (greater than or equal to 35 weeks gestation) for two geographically-defined populations of over 500,000 people. Both areas have a teaching hospital-based maternity service and comparable perinatal mortality rates. The incidence of severe post-asphyxial encephalopathy showed a marked excess in one population (1.93 vs 0.61 per 1000 births), which was not obviously explicable. Taken in conjunction with the figures for stillbirth in labour, this represented a 2.8 times greater risk for either fetal death in labour or severe asphyxial insult. It would appear that perinatal mortality rates do not accurately reflect important differences in those perinatal outcomes most likely to be affected by perinatal care.
极不成熟婴儿对围产期死亡率(PMR)的影响日益增加,这使我们质疑该参数在评估围产期护理方面的实用性。为了进一步研究这一点,我们比较了两个地理区域定义的、超过50万人的成熟婴儿(妊娠≥35周)中围产期窒息的发生率。这两个地区都有以教学医院为基础的产科服务,且围产期死亡率相当。严重窒息后脑病的发生率在其中一个人群中显著过高(每1000例出生中为1.93例 vs 0.61例),这一现象并无明显的解释。结合分娩时死产的数据,这表明分娩时胎儿死亡或严重窒息损伤的风险高出2.8倍。看来围产期死亡率并不能准确反映那些最有可能受围产期护理影响的围产期结局中的重要差异。