Brenner Allison B, Skolarus Lesli E, Perumalswami Chithra R, Burke James F
Survey Research Center, University of Michigan, Ann Arbor, Michigan, USA.
Population Health Research Director, Cascadia Behavioral Healthcare, Portland, Oregon, USA; Department of Neurology, Stroke Program, Institute for Healthcare Policy and Innovation, University of Michigan Medical School, Ann Arbor, Michigan, USA.
J Pain Symptom Manage. 2020 Sep;60(3):595-601.e3. doi: 10.1016/j.jpainsymman.2020.04.010. Epub 2020 May 4.
To determine how demographic, socioeconomic, health, and psychosocial factors predict preferences to accept life-prolonging treatments (LPTs) at the end of life (EOL).
This is a retrospective cohort study of a nationally representative sample of community-dwelling older Americans (N = 1648). Acceptance of LPT was defined as wanting to receive all LPTs in the hypothetical event of severe disability or severe chronic pain at the EOL. Participants with a durable power of attorney, living will, or who discussed EOL with family were determined to have expressed their EOL preferences. The primary analysis used survey-weighted logistic regression to measure the association between older adult characteristics and acceptance of LPT. Secondarily, the associations between LPT preferences and health outcomes were measured using regression models.
Approximately 31% of older adults would accept LPT. Nonwhite race/ethnicity (odds ratio [OR] 0.54; 95% CI 0.41, 0.70; white vs. nonwhite), self-realization (OR 1.34; 95% CI 1.01, 1.79), attendance of religious services (OR 1.44; 95% CI 1.07, 1.94), and expression of preferences (OR 0.54; 95% CI 0.40, 0.72) were associated with acceptance of LPT. LPT preferences were not independently associated with mortality or disability.
Approximately one-third of older Americans would accept LPT in the setting of severe disability or severe chronic pain at the EOL. Adults who discussed their EOL preferences were more likely to reject LPT. Conversely, minorities were more likely to accept LPT. Sociodemographics, physical capacity, and health status were poor predictors of acceptance of LPT. A better understanding of the complexities of LPT preferences is important to ensuring patient-centered care.
确定人口统计学、社会经济、健康和心理社会因素如何预测临终时接受延长生命治疗(LPT)的偏好。
这是一项对具有全国代表性的社区居住美国老年人样本(N = 1648)的回顾性队列研究。LPT的接受被定义为在临终时出现严重残疾或严重慢性疼痛的假设情况下希望接受所有LPT。拥有持久授权书、生前遗嘱或与家人讨论过临终问题的参与者被确定为已表达其临终偏好。主要分析使用调查加权逻辑回归来衡量老年人特征与接受LPT之间的关联。其次,使用回归模型衡量LPT偏好与健康结果之间的关联。
约31%的老年人会接受LPT。非白人种族/族裔(优势比[OR]0.54;95%置信区间0.41,0.70;白人vs.非白人)、自我实现(OR 1.34;95%置信区间1.01,1.79)、参加宗教仪式(OR 1.44;95%置信区间1.07,1.94)和偏好表达(OR 0.54;95%置信区间0.40,0.72)与接受LPT相关。LPT偏好与死亡率或残疾无独立关联。
约三分之一的美国老年人会在临终时出现严重残疾或严重慢性疼痛的情况下接受LPT。讨论过临终偏好的成年人更有可能拒绝LPT。相反,少数族裔更有可能接受LPT。社会人口统计学、身体能力和健康状况对接受LPT的预测性较差。更好地理解LPT偏好的复杂性对于确保以患者为中心的护理很重要。