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维生素 D 在预防 2019 年冠状病毒病感染和死亡中的作用。

The role of vitamin D in the prevention of coronavirus disease 2019 infection and mortality.

机构信息

Research and Innovation Department, The Queen Elizabeth Hospital Foundation Trust, King's Lynn, UK.

The University of East Anglia, Norfolk, UK.

出版信息

Aging Clin Exp Res. 2020 Jul;32(7):1195-1198. doi: 10.1007/s40520-020-01570-8. Epub 2020 May 6.

DOI:10.1007/s40520-020-01570-8
PMID:32377965
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7202265/
Abstract

WHO declared SARS-CoV-2 a global pandemic. The present aim was to propose an hypothesis that there is a potential association between mean levels of vitamin D in various countries with cases and mortality caused by COVID-19. The mean levels of vitamin D for 20 European countries and morbidity and mortality caused by COVID-19 were acquired. Negative correlations between mean levels of vitamin D (average 56 mmol/L, STDEV 10.61) in each country and the number of COVID-19 cases/1 M (mean 295.95, STDEV 298.7, and mortality/1 M (mean 5.96, STDEV 15.13) were observed. Vitamin D levels are severely low in the aging population especially in Spain, Italy and Switzerland. This is also the most vulnerable group of the population in relation to COVID-19. It should be advisable to perform dedicated studies about vitamin D levels in COVID-19 patients with different degrees of disease severity.

摘要

世界卫生组织宣布 SARS-CoV-2 为全球大流行病毒。本研究旨在提出一个假设,即各国维生素 D 平均水平与 COVID-19 病例和死亡率之间存在潜在关联。本研究获取了 20 个欧洲国家的维生素 D 平均水平(平均值为 56mmol/L,标准差为 10.61)以及 COVID-19 发病率和死亡率的数据。研究发现,各国维生素 D 平均水平与 COVID-19 病例数/100 万(平均值为 295.95,标准差为 298.7)和死亡率/100 万(平均值为 5.96,标准差为 15.13)之间存在负相关关系。在老龄化人口中,特别是在西班牙、意大利和瑞士,维生素 D 水平严重偏低。这也是与 COVID-19 相关的最脆弱人群。对于不同严重程度疾病的 COVID-19 患者,进行专门的维生素 D 水平研究是明智的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/018d/7202265/51cf34a30164/40520_2020_1570_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/018d/7202265/51cf34a30164/40520_2020_1570_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/018d/7202265/51cf34a30164/40520_2020_1570_Fig1_HTML.jpg

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