Institute of Food Chemistry (170b), University of Hohenheim, Garbenstraße 28, D-70599 Stuttgart, Germany.
Environmental Sciences and Management, North-West University, 2531 Potchefstroom, South Africa.
J Agric Food Chem. 2020 Jun 3;68(22):6084-6091. doi: 10.1021/acs.jafc.0c01530. Epub 2020 May 21.
Halogenated natural products (HNPs) and persistent organic pollutants (POPs) were quantified in South African sardines () from one site in the South Atlantic Ocean and one in the Indian Ocean. At both sites, HNPs [2,3,3',4,4',5,5'-heptachloro-1'-methyl-1,2'-bipyrrole (Q1), mixed halogenated compound 1 (MHC-1), 2,4,6-tribromoanisole (2,4,6-TBA), 2'-MeO-BDE 68 (BC-2), and 6-MeO-BDE 47 (BC-3)] were 1 order of magnitude higher concentrated than anthropogenic POPs [mainly polychlorinated biphenyls (PCBs) and dichlorodiphenyltrichloroethane (DDT), ∼3 ng/g lipids]. MHC-1 and Q1 were the major HNPs in the samples from both sites, contributing with up to 49 and 52 ng/g lipids, respectively. The same 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane (,'-DDE)/PCB ratio suggested that the major POPs were evenly distributed at both sites. Different ratios of Q1/MHC-1 in the samples from the Indian (∼2:1) and South Atlantic (∼1:1) Oceans indicated that the occurrence of HNPs in seafood is difficult to predict and should be investigated more in detail. The PCB levels in sardines were found to pose no risk to human consumers, whereas HNPs could not be evaluated because of the lack of toxicological data.
在南大西洋和印度洋的两个地点，对南非沙丁鱼（）中的卤代天然产物（HNPs）和持久性有机污染物（POPs）进行了定量分析。在这两个地点，HNPs[2,3,3',4,4',5,5'-七氯-1'-甲基-1,2'-联吡咯（Q1）、混合卤代化合物 1（MHC-1）、2,4,6-三溴苯甲醚（2,4,6-TBA）、2'-MeO-BDE 68（BC-2）和 6-MeO-BDE 47（BC-3）]的浓度比人为 POPs[主要为多氯联苯（PCBs）和滴滴涕（DDT），约 3ng/g 脂质]高 1 个数量级。MHC-1 和 Q1 是两个地点样品中的主要 HNPs，分别贡献了高达 49 和 52ng/g 脂质。同样的 1,1-二氯-2,2-双（4-氯苯基）乙烷（'，'-DDE/PCB 比表明，主要的 POPs 在两个地点均匀分布。印度（2:1）和南大西洋（1:1）海洋样品中 Q1/MHC-1 的比值不同，表明海产品中 HNPs 的出现难以预测，应进一步详细研究。沙丁鱼中的 PCB 水平对人类消费者没有风险，但由于缺乏毒理学数据，无法对 HNPs 进行评估。
