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血液透析带隧道导管的一种罕见并发症:上腔静脉及右心房念珠菌性心内膜炎病例报告

A rare complication of a hemodialysis tunneled catheter: Case report of a superior vena cava and right atrium candida endocarditis.

作者信息

Sousa Mariana, Martins Joana, Barreto Sara, Santos Cristina, Gouveia Rita, Santos José Paulo, Guerra Nuno, Ramos Aura

机构信息

Nephrology Department, Hospital Garcia De Orta, Almada, Portugal.

Cardiothoracic Surgery Department, Hospital Santa Maria, Lisboa, Portugal.

出版信息

IDCases. 2020 Apr 17;20:e00768. doi: 10.1016/j.idcr.2020.e00768. eCollection 2020.

Abstract

Infections remain an important cause of death among hemodialysis patients. This population have a higher risk of candidemia. Candida endocarditis it´s a rare but frequently fatal complication of candidemia. A 64 year-old female presented with a purulent discharge at the insertion site of a hemodialysis tunneled cuff catheter. A catheter related bloodstream infection was suspected, cultures were obtained and wide-spectrum antibiotic therapy was administered. A multi sensitive was isolated. Transesophageal echocardiography showed a large vegetation located in the superior vena cava, in probable relation with a previous catheter. The first approach was antifungal treatment. Due to non-response, she did a surgical removal of the vegetation. Culture of the vegetation showed the same as the blood cultures. After one year she has no signs of relapse. To improve the prognosis of this high mortality condition a high index of suspicion is necessary for early diagnosis and timely intervention.

摘要

感染仍是血液透析患者死亡的重要原因。这一人群患念珠菌血症的风险更高。念珠菌性心内膜炎是念珠菌血症一种罕见但常致命的并发症。一名64岁女性在血液透析隧道式袖套导管插入部位出现脓性分泌物。怀疑有导管相关血流感染,进行了培养并给予广谱抗生素治疗。分离出一种多重敏感菌。经食管超声心动图显示上腔静脉有一个大的赘生物,可能与先前的导管有关。首先采取抗真菌治疗。由于无反应,她接受了赘生物手术切除。赘生物培养结果与血培养相同。一年后她没有复发迹象。为改善这种高死亡率疾病的预后,早期诊断和及时干预需要高度的怀疑指数。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac60/7200829/b7fdee16c188/gr1.jpg

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