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继发于血液透析导管的感染性心内膜炎导致蛛网膜下腔出血:病例报告。

Infective endocarditis secondary to a hemodialysis catheter revealed by subarachnoid hemorrhage: Case report.

机构信息

Tunis El Manar University, Faculty of Medicine of Tunis, 1007, Tunis, Tunisia.

National Institute of Neurology of Tunis, Anesthesia-Resuscitation Department, 1007, Tunis, Tunisia.

出版信息

Tunis Med. 2024 Aug 5;102(8):496-499. doi: 10.62438/tunismed.v102i8.5022.

Abstract

INTRODUCTION

Endocarditis associated with medical care is a rare and serious entity. The risk of occurrence is increased in hemodialysis patients due to the immunosuppression and the multiplicity of vascular accesses of different kinds. The mode of revelation can be variable given the diversity of symptoms it causes. Herein, we describe the case of endocarditis associated with medical care in a patient with renal failure who presents with neurological symptoms.

OBSERVATION

A 38-year-old patient with a history of kidney disease in the hemodialysis stage presented to the emergency room with altered neurological status in the context of fever. The patient's condition requires airway control, sedation, and vasopressor medication. Brain imaging revealed Fisher 4 subarachnoid hemorrhage with brain turgor. Transthoracic and transesophageal cardiac ultrasound exploration revealed infective mitro-aortic endocarditis with trigonal abscess fistulized in the left ventricle and destruction of the aortic valve with massive regurgitation. The additional imaging in a second step did not highlight any images of mycotic aneurysm. The indication for early surgery was not approved given the hemodynamic instability and the poor intracerebral hemodynamics demonstrated by transcranial doppler ultrasound. The initial outcome under antibiotic treatment and renal replacement was favorable. But the subsequent course was fatal due to septic shock with multiple organ failure.

CONCLUSION

The diagnosis of infective endocarditis should always be considered in hemodialysis patients presenting in a septic state with signs of systemic involvement. It is a source of mortality in these debilitated patients.

摘要

引言

医疗相关性心内膜炎是一种罕见且严重的疾病。由于免疫抑制和多种不同类型的血管通路,血液透析患者发生这种疾病的风险增加。由于其引起的症状多种多样,其表现模式也可能多种多样。在此,我们描述了一例肾衰竭合并神经症状的心内膜炎患者。

观察结果

一名 38 岁的患者患有肾脏疾病,处于血液透析阶段,因发热出现神经系统改变而到急诊就诊。患者的病情需要气道控制、镇静和血管加压药物治疗。脑部影像学检查显示 Fisher 4 型蛛网膜下腔出血伴脑肿胀。经胸超声心动图和经食管超声心动图检查显示感染性二尖瓣-主动脉心内膜炎,三角脓肿瘘向左心室,主动脉瓣破坏伴大量反流。在第二步进行的其他影像学检查未发现任何真菌性动脉瘤的图像。由于经颅多普勒超声显示血流动力学不稳定和颅内血流动力学不佳,早期手术的指征未被批准。在抗生素治疗和肾脏替代治疗下,初始结果良好。但随后因感染性休克合并多器官衰竭而死亡。

结论

在出现全身受累迹象的败血症状态下,血液透析患者应始终考虑感染性心内膜炎的诊断。对于这些虚弱的患者来说,这是一种死亡原因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee32/11390058/a6ea2b44b2f4/capture1.jpg

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