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一项关于儿童社区获得性病毒性肺炎的单中心研究:2019 年 10 月至 2020 年 3 月期间无 SARS-CoV-2 证据。

A single centre study of viral community-acquired pneumonia in children: No evidence of SARS-CoV-2 from October 2019 to March 2020.

机构信息

Department of Maternal Science, Sapienza University of Rome, Rome, Italy.

Laboratory of Virology, Department of Molecular Medicine, Affiliated to Istituto Pasteur Italia - Cenci Bolognetti Foundation, Sapienza University, Rome, Italy.

出版信息

J Clin Virol. 2020 Jul;128:104385. doi: 10.1016/j.jcv.2020.104385. Epub 2020 Apr 29.

DOI:10.1016/j.jcv.2020.104385
PMID:32387967
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7189849/
Abstract

Pneumonia is an important cause of morbidity and mortality in children. We described viral aetiologies, with particular interest in detecting SARS-CoV-2, in hospitalized pneumonia children. Human rhinovirus was the most frequently detected agent. No children tested positive for SARS-CoV-2. Our findings suggest that SARS-CoV-2 infection is rare in children and it was not circulating in Rome before COVID-19 outbreak.

摘要

肺炎是导致儿童发病和死亡的重要原因。我们对住院肺炎患儿的病毒病因进行了描述,特别关注新冠病毒(SARS-CoV-2)的检测。人鼻病毒是最常被检测到的病原体。没有儿童的 SARS-CoV-2 检测结果呈阳性。我们的研究结果表明,SARS-CoV-2 感染在儿童中较为罕见,在 COVID-19 爆发之前,SARS-CoV-2 并未在罗马传播。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a415/7189849/cc0cac5f1cae/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a415/7189849/cc0cac5f1cae/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a415/7189849/cc0cac5f1cae/gr1_lrg.jpg

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Lancet Infect Dis. 2020 Jun;20(6):633-634. doi: 10.1016/S1473-3099(20)30236-X. Epub 2020 Mar 25.
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Systematic review of COVID-19 in children shows milder cases and a better prognosis than adults.系统回顾儿童 COVID-19 病例表明,其症状比成人轻,预后也更好。
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