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老年人和长寿老年人中肌少症的流行率及风险因素。

The prevalence and risk factors for sarcopenia in older adults and long-living older adults.

机构信息

Marcílio Dias Naval Hospital, Rio de Janeiro, Brazil; Federal University of Rio de Janeiro, Health Sciences Center, Institute of Nutrition, Department of Nutrition and Dietetics, Brazil.

Federal University of Rio de Janeiro, Health Sciences Center, Institute of Nutrition, Department of Social Nutrition Applied, Brazil.

出版信息

Arch Gerontol Geriatr. 2020 Jul-Aug;89:104089. doi: 10.1016/j.archger.2020.104089. Epub 2020 Apr 30.

Abstract

PURPOSE

Sarcopenia is a muscular syndrome that is related to several adverse risks. The present study aimed to evaluate the prevalence of risk of sarcopenia and associated factors in older adults and long-living older adults.

METHODS

A crosssectional epidemiological study of older adults patients at a geriatric outpatient clinic. The older adults were evaluated for sarcopenia risk using the SARC-F questionnaire supplemented with the measurement of the calf circumference. In addition, nutritional status was characterized using the Mini Nutritional Assessment, and the relationship of sarcopenia with associated factors (comorbidities, polypharmacy, smoking).

RESULTS

A total of 100 eligible older adults with a mean age of 77.2 ± 1.8 years in the older adults and 86.3 ± 4.2 years in the long-living older adults (p < 0.001) were evaluated. The long-living older adults (OR = 6.1; 95 % CI: 1.44-16.09; p = 0.01) and older adults at risk of malnutrition (OR = 13.6; 95 % CI: 1.55-11.38; p < 0.05) had a higher risk of sarcopenia, whereas BMI ≥ 27 kg/m 2 (OR = 0; 95 % CI: 0-0.06; p < 0.001) was a protective factor. The risk of sarcopenia was six times higher in the over-80 s (95 % CI = 1.44, 16.09), while the older adults with malnutrition or at nutritional risk ran a 13 times higher risk of sarcopenia (95 % CI = 1.55, 11.38).

CONCLUSION

The prevalence of risk of sarcopenia was higher in the long-living older adults and the older adults at nutritional risk, making its early evaluation in clinical practice important.

摘要

目的

肌少症是一种与多种不良风险相关的肌肉综合征。本研究旨在评估老年人和长寿老年人肌少症风险的流行情况及其相关因素。

方法

这是一项在老年门诊进行的老年人患者的横断面流行病学研究。使用 SARC-F 问卷评估老年人的肌少症风险,并辅以小腿围测量。此外,还使用 Mini Nutritional Assessment 评估营养状况,并研究肌少症与相关因素(合并症、多种药物治疗、吸烟)之间的关系。

结果

共评估了 100 名符合条件的老年人,其中老年人的平均年龄为 77.2±1.8 岁,长寿老年人的平均年龄为 86.3±4.2 岁(p<0.001)。长寿老年人(OR=6.1;95%CI:1.44-16.09;p=0.01)和有营养不良风险的老年人(OR=13.6;95%CI:1.55-11.38;p<0.05)患肌少症的风险更高,而 BMI≥27kg/m 2(OR=0;95%CI:0-0.06;p<0.001)是一个保护因素。80 岁以上老年人患肌少症的风险高 6 倍(95%CI=1.44, 16.09),而营养不良或有营养风险的老年人患肌少症的风险高 13 倍(95%CI=1.55, 11.38)。

结论

长寿老年人和有营养风险的老年人肌少症风险较高,因此在临床实践中早期评估肌少症非常重要。

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