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巴西首都高龄老年人的肌肉减少症:患病率及其相关风险因素。

Sarcopenia in the Oldest-Old Adults in the Capital of Brazil: Prevalence and Its Associated Risk Factors.

作者信息

Pinheiro Hudson Azevedo, Menezes Ruth Losada de, de Souza Cardoso Camila Kellen, da Silva Filho Rômulo Roosevelt, Registre Farah, de Oliveira César, Silveira Erika Aparecida

机构信息

Health Department of the Federal District, Brasília 72010-120, Brazil.

Study, Research, and Extension Group on Functional Health and Aging, Interdisciplinary Center on Aging, Postgraduate Program in Health Sciences, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiania 74605-050, Brazil.

出版信息

Nutrients. 2024 Nov 21;16(23):3976. doi: 10.3390/nu16233976.

Abstract

BACKGROUND

In light of the demographic context in which the older adult population is prominent, sarcopenia emerges as a significant concern for the health of these individuals.

AIM

To assess the frequency of sarcopenia and severe sarcopenia and the associated risk factors in the oldest adults living in the community.

METHODS

There were 399 participants aged 80 or older, of both sexes, using primary health care services in the metropolitan area of Brasília, Brazil. Sarcopenia was evaluated based on European Working Group on Sarcopenia in Older People 2 (EWGSOP2). Muscle mass was measured by calf circumference, muscle function by handgrip strength, and muscle performance by gait speed. Clinical and socioeconomic variables, comorbidities, falls, and urinary incontinence were collected. The prevalence of sarcopenia was calculated with a 95% (IC) prevalence. Multivariate Poisson regression analysis was performed in Stata, with < 5%.

RESULTS

Among participants, 78.2% were women. Prevalence of pre-sarcopenia was 31.8%, sarcopenia 3.3%, and severe sarcopenia 25.1%. After multivariate regression, sarcopenia was associated with the female sex, low weight, and a dependency for activities of daily living (ADLs). Similarly, severe sarcopenia remained associated with female sex, low weight, and an ADLs dependency. Sarcopenia and severe sarcopenia were not associated with the level of education, marital status, income, physical activity, medications, falls, nor comorbidities.

CONCLUSIONS

A quarter of older adults had severe sarcopenia. Sarcopenia and severe sarcopenia were associated with being a woman, being low weight, and have an ADLs dependence.

摘要

背景

鉴于老年人口占比突出的人口结构背景,肌肉减少症成为这些人群健康的重大关注点。

目的

评估社区中最年长者的肌肉减少症和严重肌肉减少症的发生率及其相关危险因素。

方法

在巴西巴西利亚大都市区使用初级卫生保健服务的399名80岁及以上的男女参与者。根据欧洲老年人肌肉减少症工作组2(EWGSOP2)评估肌肉减少症。通过小腿围测量肌肉量,通过握力测量肌肉功能,通过步速测量肌肉性能。收集临床和社会经济变量、合并症、跌倒和尿失禁情况。计算肌肉减少症的患病率及95%置信区间(IC)。在Stata中进行多变量泊松回归分析,显著性水平<5%。

结果

参与者中78.2%为女性。肌少症前期患病率为31.8%,肌肉减少症为3.3%,严重肌肉减少症为25.1%。多变量回归后,肌肉减少症与女性、低体重和日常生活活动(ADL)依赖相关。同样,严重肌肉减少症仍与女性、低体重和ADL依赖相关。肌肉减少症和严重肌肉减少症与教育水平婚姻状况、收入、身体活动、药物使用、跌倒或合并症无关。

结论

四分之一的老年人患有严重肌肉减少症。肌肉减少症和严重肌肉减少症与女性、低体重和ADL依赖有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a476/11643370/8449bb37660b/nutrients-16-03976-g001.jpg

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