Pompecki R, Erdogan S, Conic B, Frenzel H
Medizinische, Abteilung des Israelitischen Krankenhauses in Hamburg.
Z Gerontol. 1988 Sep-Oct;21(5):253-6.
In 67 patients with giant cell arteritis (GCA) and 133 control patients, the value of eight clinical parameters and five laboratory findings for the diagnosis of GCA was analyzed. Out of the clinical parameters characteristic for GCA, headaches, visual disturbance, pains of the shoulder or hip regions and fever were of diagnostic value. Of the laboratory findings, only the BSR was of diagnostic value. Inappetence, exhaustion and fatigue, although characteristic of GCA, as well as blood count, alpha-globulins, CRP and alkaline serum phosphatase were of no value in differentiating between GCA and other diseases. Each of the valuable parameters increased the probability of diagnosing GCA from 33% (incidence of GCA in our patients) up to between 48% and 52%. The simultaneous evaluation of several parameters elevated the probability of diagnosing GCA to up to 88%. These results provide a basis for a rational decision in favor of or against biopsy of the temporal artery. In the case of a negative histology, they help to decide in favor of or against long term corticoid therapy.
对67例巨细胞动脉炎（GCA）患者和133例对照患者，分析了用于GCA诊断的8项临床参数和5项实验室检查结果的价值。在GCA特有的临床参数中，头痛、视力障碍、肩部或髋部疼痛以及发热具有诊断价值。在实验室检查结果中，只有血沉（ESR）具有诊断价值。食欲不振、疲惫和乏力，尽管是GCA的特征表现，以及血细胞计数、α球蛋白、C反应蛋白（CRP）和碱性血清磷酸酶在区分GCA与其他疾病方面没有价值。每项有价值的参数将GCA的诊断概率从33%（我们患者中GCA的发病率）提高到48%至52%之间。同时评估几个参数可将GCA的诊断概率提高到88%。这些结果为就是否对颞动脉进行活检做出合理决策提供了依据。在组织学检查结果为阴性的情况下，它们有助于决定是否进行长期皮质类固醇治疗。
