Li Xin, Dai Tian, Wang Hong, Shi Junnian, Yuan Wei, Li Jing, Chen Lijun, Zhang Tianming, Zhang Shanshan, Kong Yan, Yue Ning, Shi Hui, He Yuping, Hu Huifang, Liu Furong, Yang Caixia
Fever Isolation Ward, Lanzhou University Second Hospital, Lanzhou 730030, China.
School of Public Health, Lanzhou University, Lanzhou 730000, China.
Zhejiang Da Xue Xue Bao Yi Xue Ban. 2020 May 25;49(2):203-208. doi: 10.3785/j.issn.1008-9292.2020.03.02.
To explore the risk factors of anxiety and depression in patients with suspected coronavirus disease 2019 (COVID-19) so as to achieve early intervention and better clinical prognosis.
Seventy-six patients with suspected COVID-19 in fever isolation wards of Second Hospital of Lanzhou University were enrolled From January 31, 2020 to February 22, 2020. Their clinical baseline data were collected. The anxiety of patients was assessed by Hamilton Anxiety Scale, and the depression of patients was assessed by Hamilton Depression Scale. Multivariate Logistic regression analysis was performed to explore the risk factors of anxiety and depression in these patients.
Female patients are more likely to have anxiety (=3.206, 95%: 1.073-9.583, <0.05) and depression (=9.111, 95%: 2.143-38.729, <0.01) than male patients; patients with known contact history of epidemic area and personnel in epidemic area are more likely to have depression (=3.267, 95%: 1.082-9.597, <0.05).
During the isolation treatment of suspected COVID-19 patients, early psychological intervention should be carried out for the female patients with known contact history of epidemic area and personnel in epidemic area, and drug treatment should be given in advance if necessary.
探讨2019冠状病毒病(COVID-19)疑似患者焦虑和抑郁的危险因素,以实现早期干预并获得更好的临床预后。
选取2020年1月31日至2020年2月22日在兰州大学第二医院发热隔离病房的76例COVID-19疑似患者,收集其临床基线资料。采用汉密尔顿焦虑量表评估患者的焦虑情况,采用汉密尔顿抑郁量表评估患者的抑郁情况。进行多因素Logistic回归分析,以探讨这些患者焦虑和抑郁的危险因素。
女性患者比男性患者更易出现焦虑(比值比=3.206,95%置信区间:1.073-9.583,P<0.05)和抑郁(比值比=9.111,95%置信区间:2.143-38.729,P<0.01);有疫区及疫区人员接触史的患者更易出现抑郁(比值比=3.267,95%置信区间:1.082-9.597,P<0.05)。
在COVID-19疑似患者隔离治疗期间,应对有疫区及疫区人员接触史的女性患者进行早期心理干预,必要时提前给予药物治疗。