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Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia.新型冠状病毒感染肺炎在中国武汉的早期传播动力学。
N Engl J Med. 2020 Mar 26;382(13):1199-1207. doi: 10.1056/NEJMoa2001316. Epub 2020 Jan 29.
2
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China.中国武汉地区 2019 年新型冠状病毒感染患者的临床特征。
Lancet. 2020 Feb 15;395(10223):497-506. doi: 10.1016/S0140-6736(20)30183-5. Epub 2020 Jan 24.
3
A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster.一个涉及 2019 年新型冠状病毒的家庭聚集性肺炎病例,提示存在人际传播:一项家庭聚集性研究。
Lancet. 2020 Feb 15;395(10223):514-523. doi: 10.1016/S0140-6736(20)30154-9. Epub 2020 Jan 24.
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A novel coronavirus outbreak of global health concern.一场引发全球卫生关注的新型冠状病毒疫情。
Lancet. 2020 Feb 15;395(10223):470-473. doi: 10.1016/S0140-6736(20)30185-9. Epub 2020 Jan 24.
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A Novel Coronavirus from Patients with Pneumonia in China, 2019.2019 年中国肺炎患者中的一种新型冠状病毒。
N Engl J Med. 2020 Feb 20;382(8):727-733. doi: 10.1056/NEJMoa2001017. Epub 2020 Jan 24.
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A Novel Coronavirus Emerging in China - Key Questions for Impact Assessment.一种在中国出现的新型冠状病毒——影响评估的关键问题
N Engl J Med. 2020 Feb 20;382(8):692-694. doi: 10.1056/NEJMp2000929. Epub 2020 Jan 24.
7
Coronavirus Infections-More Than Just the Common Cold.冠状病毒感染——远不止是普通感冒。
JAMA. 2020 Feb 25;323(8):707-708. doi: 10.1001/jama.2020.0757.
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The immediate psychological and occupational impact of the 2003 SARS outbreak in a teaching hospital.2003年非典疫情在一家教学医院造成的即时心理和职业影响。
CMAJ. 2003 May 13;168(10):1245-51.
9
How safe are serotonin reuptake inhibitors for depression in patients with coronary heart disease?5-羟色胺再摄取抑制剂用于冠心病患者治疗抑郁症时的安全性如何?
Am J Med. 1997 Jan;102(1):54-9. doi: 10.1016/s0002-9343(96)00374-9.
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Differences between males and females in rates of serotonin synthesis in human brain.人类大脑中血清素合成速率的性别差异。
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[新型冠状病毒肺炎疑似患者焦虑抑郁状况的临床分析]

[Clinical analysis of suspected COVID-19 patients with anxiety and depression].

作者信息

Li Xin, Dai Tian, Wang Hong, Shi Junnian, Yuan Wei, Li Jing, Chen Lijun, Zhang Tianming, Zhang Shanshan, Kong Yan, Yue Ning, Shi Hui, He Yuping, Hu Huifang, Liu Furong, Yang Caixia

机构信息

Fever Isolation Ward, Lanzhou University Second Hospital, Lanzhou 730030, China.

School of Public Health, Lanzhou University, Lanzhou 730000, China.

出版信息

Zhejiang Da Xue Xue Bao Yi Xue Ban. 2020 May 25;49(2):203-208. doi: 10.3785/j.issn.1008-9292.2020.03.02.

DOI:10.3785/j.issn.1008-9292.2020.03.02
PMID:32391665
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8800785/
Abstract

OBJECTIVE

To explore the risk factors of anxiety and depression in patients with suspected coronavirus disease 2019 (COVID-19) so as to achieve early intervention and better clinical prognosis.

METHODS

Seventy-six patients with suspected COVID-19 in fever isolation wards of Second Hospital of Lanzhou University were enrolled From January 31, 2020 to February 22, 2020. Their clinical baseline data were collected. The anxiety of patients was assessed by Hamilton Anxiety Scale, and the depression of patients was assessed by Hamilton Depression Scale. Multivariate Logistic regression analysis was performed to explore the risk factors of anxiety and depression in these patients.

RESULTS

Female patients are more likely to have anxiety (=3.206, 95%: 1.073-9.583, <0.05) and depression (=9.111, 95%: 2.143-38.729, <0.01) than male patients; patients with known contact history of epidemic area and personnel in epidemic area are more likely to have depression (=3.267, 95%: 1.082-9.597, <0.05).

CONCLUSIONS

During the isolation treatment of suspected COVID-19 patients, early psychological intervention should be carried out for the female patients with known contact history of epidemic area and personnel in epidemic area, and drug treatment should be given in advance if necessary.

摘要

目的

探讨2019冠状病毒病(COVID-19)疑似患者焦虑和抑郁的危险因素,以实现早期干预并获得更好的临床预后。

方法

选取2020年1月31日至2020年2月22日在兰州大学第二医院发热隔离病房的76例COVID-19疑似患者,收集其临床基线资料。采用汉密尔顿焦虑量表评估患者的焦虑情况,采用汉密尔顿抑郁量表评估患者的抑郁情况。进行多因素Logistic回归分析,以探讨这些患者焦虑和抑郁的危险因素。

结果

女性患者比男性患者更易出现焦虑(比值比=3.206,95%置信区间:1.073-9.583,P<0.05)和抑郁(比值比=9.111,95%置信区间:2.143-38.729,P<0.01);有疫区及疫区人员接触史的患者更易出现抑郁(比值比=3.267,95%置信区间:1.082-9.597,P<0.05)。

结论

在COVID-19疑似患者隔离治疗期间,应对有疫区及疫区人员接触史的女性患者进行早期心理干预,必要时提前给予药物治疗。