Suppr超能文献

因诺琴蒂停用的发生率和决定因素:来自刚果民主共和国金沙萨三个卫生区的前瞻性队列研究结果。

Incidence and determinants of Implanon discontinuation: Findings from a prospective cohort study in three health zones in Kinshasa, DRC.

机构信息

Kinshasa School of Public Health, University of Kinshasa, Kinshasa, the Democratic Republic of the Congo.

School of Public Health and Tropical Medicine, Tulane University, New Orleans, Louisiana, United States of America.

出版信息

PLoS One. 2020 May 11;15(5):e0232582. doi: 10.1371/journal.pone.0232582. eCollection 2020.

Abstract

BACKGROUND

Kinshasa is Africa's third largest city and one of the continent's most rapidly growing urban areas. PMA2020 data showed that Kinshasa has a modern contraceptive prevalence of 26.5% among married women in 2018. In Kinshasa's method mix, the contraceptive implant recently became the dominant method among contraceptive users married and in union. This study provides insight into patterns of implant use in a high-fertility setting by evaluating the 24-month continuation rate for Implanon NXT and identifying the characteristics associated with discontinuation.

METHODOLOGY

This community-based, prospective cohort study followed 531 Implanon users aged 18-49 years at 6, 12 and 24 months. The following information was collected: socio-demographic characteristics, Method Information Index (MII) and contraceptive history. The main outcome variable for this study was implant discontinuation. The incidence rate of discontinuation is presented as events per 1000 person/months (p-m), from the date of enrolment. The Cox proportional hazards modelling was used to measure predictors of discontinuation.

RESULTS

A total of 9158.13 p-m were available for analysis, with an overall incidence rate of 9.06 (95% CI: 9.04-9.08) removals per 1000 p-m. Of nine possible co-variates tested, the likelihood of discontinuation was higher among women who lived in military camps, had less than three children, never used injectables or implants in the past, had experienced heavy/prolonged bleeding, and whose MII score was less than 3.

CONCLUSION

In addition to four client characteristics that predicted discontinuation, we identified one programmatic factor: quality of counseling as measured by the Method Information Index. Community providers in similar contexts should pay more attention to clients having less than three children, new adopters, and to clients living military camps as underserved population, where clients have less access to health facilities. More targeted counselling and follow-up is needed, especially on bleeding patterns.

摘要

背景

金沙萨是非洲第三大城市,也是非洲大陆发展最快的城市之一。2020 年人口与生殖健康调查数据显示,2018 年,金沙萨已婚育龄妇女的现代避孕方法使用率为 26.5%。在金沙萨的避孕方法组合中,避孕植入物最近成为已婚和同居的避孕使用者中最主要的方法。本研究通过评估 Implanon NXT 的 24 个月续用率,并确定与停药相关的特征,深入了解高生育率环境下植入物使用模式。

方法

本基于社区的前瞻性队列研究随访了 531 名年龄在 18-49 岁的 Implanon 用户,随访时间为 6、12 和 24 个月。收集了以下信息:社会人口统计学特征、方法信息指数(MII)和避孕史。本研究的主要结局变量是植入物的停药。从登记日期开始,每 1000 人/月(p-m)的停药事件数表示停药发生率。使用 Cox 比例风险模型来衡量停药的预测因素。

结果

共获得 9158.13 p-m 用于分析,总停药发生率为 9.06(95%CI:9.04-9.08)/1000 p-m。在测试的九个可能的协变量中,以下因素的停药可能性更高:居住在军营中的女性、生育少于三个孩子的女性、过去从未使用过注射剂或植入剂的女性、经历过大量/长时间出血的女性,以及 MII 评分低于 3 的女性。

结论

除了四个预测停药的客户特征外,我们还确定了一个方案因素:方法信息指数衡量的咨询质量。类似背景下的社区服务提供者应更加关注生育少于三个孩子的客户、新采用者,以及居住在军营中的客户等服务不足的人群,这些人群获得卫生设施的机会较少。需要进行更有针对性的咨询和随访,特别是在出血模式方面。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab38/7213683/d7789bb55d54/pone.0232582.g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验