3D 打印用于神经介入的模型的设计和物理特性：文献的系统评价。
Design and Physical Properties of 3-Dimensional Printed Models Used for Neurointervention: A Systematic Review of the Literature.
机构信息
Department of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York.
Department of Neurosurgery, Gates Vascular Institute at Kaleida Health, Buffalo, New York.
出版信息
Neurosurgery. 2020 Sep 15;87(4):E445-E453. doi: 10.1093/neuros/nyaa134.
BACKGROUND
Three-dimensional (3D) printing has revolutionized training, education, and device testing. Understanding the design and physical properties of 3D-printed models is important.
OBJECTIVE
To systematically review the design, physical properties, accuracy, and experimental outcomes of 3D-printed vascular models used in neurointervention.
METHODS
We conducted a systematic review of the literature between January 1, 2000 and September 30, 2018. Public/Publisher MEDLINE (PubMed), Web of Science, Compendex, Cochrane, and Inspec databases were searched using Medical Subject Heading terms for design and physical attributes of 3D-printed models for neurointervention. Information on design and physical properties like compliance, lubricity, flow system, accuracy, and outcome measures were collected.
RESULTS
A total of 23 articles were included. Nine studies described 3D-printed models for stroke intervention. Tango Plus (Stratasys) was the most common material used to develop these models. Four studies described a population-representative geometry model. All other studies reported patient-specific vascular geometry. Eight studies reported complete reconstruction of the circle of Willis, anterior, and posterior circulation. Four studies reported a model with extracranial vasculature. One prototype study reported compliance and lubricity. Reported circulation systems included manual flushing, programmable pistons, peristaltic, and pulsatile pumps. Outcomes included thrombolysis in cerebral infarction, post-thrombectomy flow restoration, surgical performance, and qualitative feedback.
CONCLUSION
Variations exist in the material, design, and extent of reconstruction of vasculature of 3D-printed models. There is a need for objective characterization of 3D-printed vascular models. We propose the development of population representative 3D-printed models for skill improvement or device testing.
背景
三维（3D）打印技术已经彻底改变了培训、教育和设备测试。了解 3D 打印模型的设计和物理特性非常重要。
目的
系统回顾神经介入中使用的 3D 打印血管模型的设计、物理特性、准确性和实验结果。
方法
我们对 2000 年 1 月 1 日至 2018 年 9 月 30 日期间的文献进行了系统回顾。使用医学主题词搜索了公共/出版商 MEDLINE（PubMed）、Web of Science、Compendex、Cochrane 和 Inspec 数据库，以获取用于神经介入的 3D 打印模型的设计和物理属性的信息。收集了有关设计和物理特性的信息，如顺应性、润滑性、流动系统、准确性和结果测量。
结果
共纳入 23 篇文章。9 项研究描述了用于卒中干预的 3D 打印模型。Tango Plus（Stratasys）是开发这些模型最常用的材料。4 项研究描述了具有代表性的人群几何模型。所有其他研究均报告了患者特定的血管几何形状。8 项研究报告了完整的 Willis 环、前循环和后循环重建。4 项研究报告了颅外血管模型。1 项原型研究报告了顺应性和润滑性。报告的循环系统包括手动冲洗、可编程活塞、蠕动和脉动泵。结果包括脑梗死溶栓、血栓切除后血流恢复、手术性能和定性反馈。
结论
3D 打印模型的血管材料、设计和重建程度存在差异。需要对 3D 打印血管模型进行客观表征。我们建议开发具有代表性的人群 3D 打印模型，以提高技能或进行设备测试。
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