Department of Medical Radiation Sciences, Curtin University, GPO Box U1987, Perth, Western Australia, 6845, Australia.
J Digit Imaging. 2018 Oct;31(5):692-701. doi: 10.1007/s10278-018-0067-x.
The purpose of this review is to analyse current literature related to the clinical applications of 3D printed models in liver disease. A search of the literature was conducted to source studies from databases with the aim of determining the applications and feasibility of 3D printed models in liver disease. 3D printed model accuracy and costs associated with 3D printing, the ability to replicate anatomical structures and delineate important characteristics of hepatic tumours, and the potential for 3D printed liver models to guide surgical planning are analysed. Nineteen studies met the selection criteria for inclusion in the analysis. Seventeen of them were case reports and two were original studies. Quantitative assessment measuring the accuracy of 3D printed liver models was analysed in five studies with mean difference between 3D printed models and original source images ranging from 0.2 to 20%. Fifteen studies provided qualitative assessment with results showing the usefulness of 3D printed models when used as clinical tools in preoperative planning, simulation of surgical or interventional procedures, medical education, and training. The cost and time associated with 3D printed liver model production was reported in 11 studies, with costs ranging from US$13 to US$2000, duration of production up to 100 h. This systematic review shows that 3D printed liver models demonstrate hepatic anatomy and tumours with high accuracy. The models can assist with preoperative planning and may be used in the simulation of surgical procedures for the treatment of malignant hepatic tumours.
本综述旨在分析目前与肝脏疾病中 3D 打印模型的临床应用相关的文献。通过对文献进行检索，以确定 3D 打印模型在肝脏疾病中的应用和可行性。本文分析了 3D 打印模型的准确性和 3D 打印的成本、复制解剖结构和描绘肝脏肿瘤重要特征的能力，以及 3D 打印肝脏模型在指导手术规划方面的潜力。19 项研究符合纳入分析的标准。其中 17 项为病例报告，2 项为原始研究。五项研究对 3D 打印肝脏模型的准确性进行了定量评估，3D 打印模型与原始源图像之间的平均差异范围为 0.2 至 20%。15 项研究提供了定性评估结果，表明 3D 打印模型在术前规划、手术或介入程序模拟、医学教育和培训等临床工具中具有实用性。11 项研究报告了 3D 打印肝脏模型制作的成本和时间，成本范围从 13 美元到 2000 美元不等，制作时间长达 100 小时。本系统评价表明，3D 打印肝脏模型可以准确地显示肝脏解剖结构和肿瘤。这些模型可以帮助进行术前规划，并可用于模拟治疗恶性肝脏肿瘤的手术程序。
