Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Immunity. 2020 May 19;52(5):734-736. doi: 10.1016/j.immuni.2020.04.016. Epub 2020 May 8.
The emergence and rapid global spread of SARS-CoV-2 mark the third such identification of a novel coronavirus capable of causing severe, potentially fatal disease in humans in the 21 century. As noted by Andersen et al. (Nature Medicine), the sequencing of proximal zoonotic ancestors to SARS-CoV-2 has aided in the identification of alleles that may contribute to the virus' virulence in humans.
SARS-CoV-2 的出现和迅速在全球范围内传播标志着第三个能够导致人类严重、潜在致命疾病的新型冠状病毒的发现。正如 Andersen 等人在《自然医学》中所指出的，对 SARS-CoV-2 最近的动物源祖先进行测序有助于确定可能导致该病毒在人类中毒力的等位基因。
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