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光动力疗法在牙科中的应用:当前概念

Utility of Photodynamic Therapy in Dentistry: Current Concepts.

作者信息

Stájer Anette, Kajári Szilvia, Gajdács Márió, Musah-Eroje Aima, Baráth Zoltán

机构信息

Department of Periodontology, Faculty of Dentistry, University of Szeged, Tiszta Lajos körút 62-64, 6720 Szeged, Hungary.

Department of Pharmacodynamics and Biopharmacy, Faculty of Pharmacy, University of Szeged, Eötvös utca 6., 6720 Szeged, Hungary.

出版信息

Dent J (Basel). 2020 May 7;8(2):43. doi: 10.3390/dj8020043.

Abstract

The significant growth in scientific and technological advancements within the field of dentistry has resulted in a wide range of novel treatment modalities for dentists to use. Photodynamic therapy (PDT) is an emerging, non-invasive treatment method, involving photosensitizers, light of a specific wavelength and the generation of singlet oxygen and reactive oxygen species (ROS) to eliminate unwanted eukaryotic cells (e.g., malignancies in the oral cavity) or pathogenic microorganisms. The aim of this review article is to summarize the history, general concepts, advantages and disadvantages of PDT and to provide examples for current indications of PDT in various subspecialties of dentistry (oral and maxillofacial surgery, oral medicine, endodontics, preventive dentistry, periodontology and implantology), in addition to presenting some images from our own experiences about the clinical success with PDT.

摘要

牙科领域科技进步的显著增长,为牙医带来了广泛的新型治疗方式。光动力疗法(PDT)是一种新兴的非侵入性治疗方法,涉及光敏剂、特定波长的光以及单线态氧和活性氧(ROS)的产生,以消除不需要的真核细胞(如口腔恶性肿瘤)或致病微生物。这篇综述文章的目的是总结光动力疗法的历史、一般概念、优缺点,并举例说明光动力疗法在牙科各个亚专业(口腔颌面外科、口腔内科、牙髓病学、预防牙科、牙周病学和种植学)中的当前适应证,此外还展示了我们自己在光动力疗法临床成功经验中的一些图像。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/324c/7345245/6e5980b4e93a/dentistry-08-00043-g001.jpg

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