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地高辛治疗后依赖胎儿房性心动过速持续存在而缓解的胎儿水肿。

Resolution of Fetal Hydrops Dependent on Sustained Fetal Supraventricular Tachycardia after Digoxin Therapy.

机构信息

Department of Obstetrics and Gynecology, Lithuanian University of Health Sciences, LT-50161 Kaunas, Lithuania.

Department of Cardiology, Lithuanian University of Health Sciences, LT-50161 Kaunas, Lithuania.

出版信息

Medicina (Kaunas). 2020 May 7;56(5):223. doi: 10.3390/medicina56050223.

DOI:10.3390/medicina56050223
PMID:32392830
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7279374/
Abstract

We present a special case of fetal supraventricular tachycardia detected at 34 weeks gestation. Fetal hydrops was noted on ultrasound upon admission. Normal fetal heart rate was maintained for three weeks by maternal administration of digoxin. A live infant was delivered via caesarian section at 37 weeks gestation. This clinical case demonstrated that pharmacological treatment can be effective and helps to prolong pregnancy safely.

摘要

我们呈现了一例特殊的胎儿室上性心动过速病例,该病例于 34 周妊娠时被检出。入院时超声检查提示胎儿水肿。通过母亲给予地高辛治疗,胎儿心率在 3 周内保持正常。患儿于 37 周时经剖宫产娩出,为活婴。本临床病例表明,药物治疗可能有效,并有助于安全延长妊娠时间。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a075/7279374/0865b8fc142e/medicina-56-00223-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a075/7279374/8e6f15faca84/medicina-56-00223-g0A1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a075/7279374/e6c0e83014a5/medicina-56-00223-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a075/7279374/0865b8fc142e/medicina-56-00223-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a075/7279374/8e6f15faca84/medicina-56-00223-g0A1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a075/7279374/e6c0e83014a5/medicina-56-00223-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a075/7279374/0865b8fc142e/medicina-56-00223-g002.jpg

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本文引用的文献

1
First-Line Antiarrhythmic Transplacental Treatment for Fetal Tachyarrhythmia: A Systematic Review and Meta-Analysis.一线抗心律失常药物经胎盘治疗胎儿心动过速:系统评价和荟萃分析。
J Am Heart Assoc. 2017 Dec 15;6(12):e007164. doi: 10.1161/JAHA.117.007164.
2
Flecainide versus digoxin for fetal supraventricular tachycardia: Comparison of two drug treatment protocols.氟卡尼与地高辛治疗胎儿室上性心动过速:两种药物治疗方案的比较。
Heart Rhythm. 2016 Sep;13(9):1913-9. doi: 10.1016/j.hrthm.2016.03.023.
3
Digoxin Therapy of Fetal Superior Ventricular Tachycardia: Are Digoxin Serum Levels Reliable?
地高辛治疗胎儿室上性心动过速:地高辛血清水平可靠吗?
AJP Rep. 2016 Jul;6(3):e272-6. doi: 10.1055/s-0036-1586241.
4
Diagnosis and treatment of fetal cardiac disease: a scientific statement from the American Heart Association.胎儿心脏疾病的诊断与治疗:美国心脏协会科学声明
Circulation. 2014 May 27;129(21):2183-242. doi: 10.1161/01.cir.0000437597.44550.5d. Epub 2014 Apr 24.
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Fetal diagnosis and imaging in cardiology.胎儿心脏病诊断与影像学
Expert Opin Med Diagn. 2008 Nov;2(11):1291-307. doi: 10.1517/17530059.2.11.1291.
6
Effectiveness of sotalol as first-line therapy for fetal supraventricular tachyarrhythmias.索他洛尔作为胎儿室上性心动过速一线治疗的疗效。
Am J Cardiol. 2012 Jun 1;109(11):1614-8. doi: 10.1016/j.amjcard.2012.01.388. Epub 2012 Mar 22.
7
Fetal arrhythmia: prenatal diagnosis and perinatal management.胎儿心律失常:产前诊断与围产期管理
J Obstet Gynaecol Res. 2009 Aug;35(4):623-9. doi: 10.1111/j.1447-0756.2009.01080.x.
8
Resolution of hydrops fetalis despite persistent fetal tachycardia.
J Ultrasound Med. 2001 Oct;20(10):1141-5. doi: 10.7863/jum.2001.20.10.1141.
9
Is hospital admission for initiation of antiarrhythmic therapy with sotalol for atrial arrhythmias required? Yield of in-hospital monitoring and prediction of risk for significant arrhythmia complications.使用索他洛尔启动抗心律失常治疗以治疗房性心律失常是否需要住院?住院监测的收益及严重心律失常并发症风险的预测。
J Am Coll Cardiol. 1998 Jul;32(1):169-76. doi: 10.1016/s0735-1097(98)00189-2.