Faculty of Medicine, Universitas Indonesia, No. 6, Salemba Raya Road, DKI Jakarta, 10430, Indonesia.
Department of Urology, Cipto Mangunkusumo National Hospital, Diponegoro Road, DKI Jakarta, 10430, Indonesia.
Int J Impot Res. 2021 Jul;33(5):516-524. doi: 10.1038/s41443-020-0298-5. Epub 2020 May 11.
Lower urinary tract symptoms (LUTS) refer to a group of symptoms related to bladder, prostate, and urethra. LUTS are common in men and the severity increases with age. LUTS are frequently associated with sexual dysfunction, such as premature ejaculation (PE), standing as the most common sexual dysfunction in men. Both LUTS and PE cause distress and dissatisfaction for the patient and his partner. This systematic review aims to determine the relationship between LUTS and PE in men. Two reviewers independently conduct a literature search in five online databases (PubMed, Scopus, Proquest, ClinicalKey, and ScienceDirect). In addition, reviewers also reviewed the reference list of chosen articles to identify additional relevant studies. Twelve articles were included in this systematic review that consists of one cohort study and 11 cross-sectional studies. The total scores of each identified study ranged from "poor" to "good." The prevalence of PE in LUTS ranged from 12 to 77%. Most of the studies showed a significant relationship between LUTS and PE. PE is more common in older age with the peak prevalence in age of 60-69 years old. There is a possible association between PE and LUTS. Further research using cohort or case-control study design on this topic is needed.
下尿路症状 (LUTS) 是指与膀胱、前列腺和尿道相关的一组症状。LUTS 在男性中很常见，且严重程度随年龄增长而增加。LUTS 常与性功能障碍相关，如早泄 (PE)，PE 是男性最常见的性功能障碍。LUTS 和 PE 都会给患者及其伴侣带来痛苦和不满。本系统评价旨在确定男性 LUTS 和 PE 之间的关系。两名审查员独立在五个在线数据库（PubMed、Scopus、Proquest、ClinicalKey 和 ScienceDirect）中进行文献检索。此外，审查员还查阅了选定文章的参考文献，以确定其他相关研究。本系统评价共纳入 12 篇文章，包括 1 项队列研究和 11 项横断面研究。每个确定研究的总评分范围为“差”至“良好”。LUTS 中 PE 的患病率从 12%到 77%不等。大多数研究表明 LUTS 和 PE 之间存在显著关系。PE 在年龄较大时更为常见，60-69 岁时的患病率最高。PE 和 LUTS 之间可能存在关联。需要对此主题进行进一步的队列或病例对照研究。
