Post-Graduate School of Occupational Health, Università Cattolica del Sacro Cuore, Rome, Italy.
Department of Woman/Child & Public Health Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Occup Med (Lond). 2020 Sep 9;70(6):442-444. doi: 10.1093/occmed/kqaa068.
Systemic sclerosis is a potentially devastating disease in which the aetiology and pathogenesis has not yet been fully understood. It has been associated with occupational exposure to silica, vinyl chloride, solvents and other chemical agents.
In this paper, we present the case of an anaesthetist who developed scleroderma after an occupational exposure to volatile anaesthetic gases (halothane, sevoflurane, isoflurane and enflurane) in operating theatres with poor scavenging systems and we discuss the possible causal link between occupational exposure and the disease.
The case reported is the second that we are aware of in recent years. Reporting scleroderma cases in workers may be the first step in assessing the causal link between occupational exposure to anaesthetic gases and the disease.
系统性硬化症是一种潜在的破坏性疾病，其病因和发病机制尚未完全阐明。它与职业性接触二氧化硅、氯乙烯、溶剂和其他化学物质有关。
本文报道了一名麻醉师在手术室中接触挥发性麻醉气体（氟烷、七氟烷、异氟烷和恩氟烷），且手术室通风不良，发生职业性暴露后出现硬皮病的病例，并讨论了职业性暴露与疾病之间可能的因果关系。
报告的病例是近年来我们所知的第二例。报告职业性接触麻醉气体与疾病相关的硬皮病病例可能是评估两者之间因果关系的第一步。
