Roll M, Perski A, Theorell T
Department of Medicine, Danderyd Hospital, Sweden.
Acta Med Scand. 1988;224(3):237-43. doi: 10.1111/j.0954-6820.1988.tb19367.x.
Reactivity to mental stress and relaxation was studied in 63 consecutive patients below the age of 40 attending the emergency care unit because of chest pain without obvious organic cause. The results were compared with a control group (n = 32). Of the patients, 41% reported chest pain or oppression in the chest during mental stress compared to 10% of the control subjects (p less than 0.01). During relaxation the subjects in the female patient group reported significantly less ability to relax and had significantly higher respiration rate as compared to the female control group. There were no significant differences between the groups regarding heart rate, blood pressure or end-tidal PCO2 and there was no evidence of hyperventilation, neither during relaxation nor during mental stress. In combination with our earlier findings of high scores for "type A behaviour", "neuroticism", "vital exhaustion" and "stressful life events" these findings indicate that psychosomatic mechanisms may be of great importance for the development of chest pain in this group of patients.
对63名年龄在40岁以下因胸痛前来急诊且无明显器质性病因的连续患者进行了心理应激和放松反应的研究。将结果与一个对照组（n = 32）进行比较。在这些患者中，41%的人在心理应激期间报告有胸痛或胸部压迫感，而对照组中这一比例为10%（p < 0.01）。在放松过程中，女性患者组的受试者报告称放松能力明显较差，且与女性对照组相比呼吸频率明显更高。两组在心率、血压或呼气末二氧化碳分压方面无显著差异，且在放松或心理应激期间均无过度通气的证据。结合我们之前关于“A型行为”“神经质”“职业倦怠”和“应激性生活事件”得分较高的研究结果，这些发现表明，心身机制可能对这组患者胸痛的发生具有重要意义。
