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药用植物中的放射性核素浓度和通过阿育吠陀药物摄入的有效剂量。

Radionuclide concentrations in medicinal florae and committed effective dose through Ayurvedic medicines.

机构信息

Center for Advanced Research in Physical Sciences, Department of Physics, Fatima Mata National College (Autonomous), Kollam, India.

Department of Applied Physics, The Papua New Guinea University of Technology, Lae, Morobe, Papua New Guinea.

出版信息

Int J Radiat Biol. 2020 Aug;96(8):1028-1037. doi: 10.1080/09553002.2020.1767816. Epub 2020 Jun 8.

DOI:10.1080/09553002.2020.1767816
PMID:32394771
Abstract

Ayurveda is one of the oldest systems of medicines in the world being practiced widely in the Indian subcontinent for more than 3000 years, and still remains as one of the important traditional health care systems. The Ayurvedic drugs are derived primarily from various parts of the plants, like root, leaf, flower, fruit or plant as a whole. Plants uptake minerals and other nutrients from the soil through their root system. Along with other minerals radionuclides present in the growing media also reach to the plant parts following the same pathway. Realizing the probable health hazards via the intake of Ayurvedic drugs, it is important to assess the concentration of natural radionuclides in commonly used medicinal plants. NaI(Tl) scintillator-based gamma-ray spectrometry has been used to determine the activity concentrations of primordial radionuclides (Ra, Th and K) in the most commonly used medicinal plant parts as ingredients of Ayurvedic medicines in India. The average specific activity (Bqkg) of Ra, Th and K was found to be 43 ± 18, 36 ± 15[Formula: see text] and 230 ± 46, respectively. The estimated annual committed effective doses due to the intake of common Ayurvedic medicines at prescribed dosage was found to be 39 ± 16 Sv y,[Formula: see text] which is quite low as compared with the radiation dose limit of 1 mSvy from all natural sources, reported by the International Commission on Radiological Protection (ICRP-60). It is found categorically that intake of Ayurvedic medicines at normal dosage poses no radiological hazard to the individual. Present results are significant in the wake of myths that many hazardous materials including radioisotopes are present at higher levels. Obtained results also serve as a reference information for the distribution of radionuclides in medicinal plant species.

摘要

阿育吠陀是世界上最古老的医学体系之一,在印度次大陆已经广泛应用了 3000 多年,仍然是重要的传统保健体系之一。阿育吠陀药物主要来源于植物的各个部分,如根、叶、花、果实或整株植物。植物通过根系从土壤中吸收矿物质和其他养分。与其他矿物质一样,生长介质中存在的放射性核素也会沿着相同的途径到达植物部分。意识到通过摄入阿育吠陀药物可能带来的健康危害,评估常用药用植物中天然放射性核素的浓度非常重要。基于碘化钠 (Tl) 闪烁体的伽马射线光谱法已用于测定印度常用药用植物部分作为阿育吠陀药物成分的原始放射性核素(Ra、Th 和 K)的活度浓度。Ra、Th 和 K 的平均比活度(Bqkg)分别为 43±18、36±15[公式:见正文]和 230±46。根据规定剂量摄入常见阿育吠陀药物导致的年估计有效剂量为 39±16 Sv y,[公式:见正文]与国际辐射防护委员会 (ICRP-60) 报告的来自所有天然来源的 1 mSvy 辐射剂量限值相比,这是相当低的。可以明确地说,正常剂量摄入阿育吠陀药物对个人没有放射性危害。鉴于存在许多危险材料,包括放射性同位素的含量较高的说法,本研究结果具有重要意义。获得的结果也为药用植物种属中放射性核素的分布提供了参考信息。

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