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视神经病变鉴别诊断中的布鲁赫膜开口最小边缘宽度

Bruch's Membrane Opening Minimum Rim Width in the Differential Diagnosis of Optic Neuropathies.

作者信息

Braga Joana, Soares Ricardo, Loureiro Mónica, Ribeiro Lígia, Meira Dália

机构信息

Ophthalmology Department, Centro Hospitalar Vila Nova de Gaia/Espinho, EPE, Porto, Portugal.

出版信息

Neuroophthalmology. 2019 Aug 21;44(2):76-88. doi: 10.1080/01658107.2019.1650075. eCollection 2020 Apr.

DOI:10.1080/01658107.2019.1650075
PMID:32395154
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7202433/
Abstract

Observing optic disc pallor during a patient's first visit frequently raises a diagnostic challenge, particularly in regards to whether the cause is due to glaucoma or another form of optic neuropathy. Bruch's membrane opening (BMO) was recently discovered as the anatomical border of the optic disc. BMO minimum rim width (BMO-MRW) seems to be a reliable representation of the neuroretinal rim. In our study, we demonstrate the ability of BMO-MRWs to differentiate between glaucomatous and non-glaucomatous. Additionally, we propose an MRW ratio which may allow discrimination of open angle glaucoma from either non-arteritic anterior ischaemic optic neuropathy or compressive optic neuropathy.

摘要

在患者首次就诊时观察到视盘苍白常常会带来诊断挑战,尤其是在确定病因是青光眼还是其他形式的视神经病变方面。布鲁赫膜开口(BMO)最近被发现是视盘的解剖学边界。BMO最小边缘宽度(BMO-MRW)似乎是神经视网膜边缘的可靠指标。在我们的研究中,我们展示了BMO-MRW区分青光眼性和非青光眼性病变的能力。此外,我们提出了一种MRW比率,它可能有助于从非动脉性前部缺血性视神经病变或压迫性视神经病变中鉴别开角型青光眼。

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Bruch's Membrane Opening Minimum Rim Width in the Differential Diagnosis of Optic Neuropathies.视神经病变鉴别诊断中的布鲁赫膜开口最小边缘宽度
Neuroophthalmology. 2019 Aug 21;44(2):76-88. doi: 10.1080/01658107.2019.1650075. eCollection 2020 Apr.
2
Novel Bruch's Membrane Opening Minimum Rim Area Equalizes Disc Size Dependency and Offers High Diagnostic Power for Glaucoma.新型布鲁赫膜开口最小边缘面积可平衡视盘大小依赖性并为青光眼提供高诊断效能。
Invest Ophthalmol Vis Sci. 2016 Dec 1;57(15):6596-6603. doi: 10.1167/iovs.16-20561.
3
Bruch's Membrane Opening Minimum Rim Width Provides Objective Differentiation between Glaucoma and Nonglaucomatous Optic Neuropathies.Bruch 膜开口最小 rim 宽度为青光眼和非青光眼视神经病变的客观鉴别提供依据。
Am J Ophthalmol. 2020 Oct;218:164-172. doi: 10.1016/j.ajo.2020.05.034. Epub 2020 Jun 20.
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Comparison of glaucomatous from non-glaucomatous optic neuropathy using Bruch's membrane opening minimum rim width optical coherence tomography measurements.比较使用 Bruch 膜开口最小边缘宽度光相干断层扫描测量的青光眼性和非青光眼性视神经病变。
Indian J Ophthalmol. 2023 Aug;71(8):3005-3009. doi: 10.4103/IJO.IJO_3171_22.
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Neuroretinal rim in non-glaucomatous large optic nerve heads: a comparison of confocal scanning laser tomography and spectral domain optical coherence tomography.非青光眼性大视乳头的神经视网膜边缘:共焦扫描激光断层扫描与光谱域光学相干断层扫描的比较
Br J Ophthalmol. 2017 Feb;101(2):138-142. doi: 10.1136/bjophthalmol-2015-307730. Epub 2016 Apr 26.
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Association of Bruch's membrane opening and optic disc morphology to axial length and visual field defects in eyes with primary open-angle glaucoma.原发性开角型青光眼患者眼中布鲁赫膜开口及视盘形态与眼轴长度和视野缺损的相关性
Graefes Arch Clin Exp Ophthalmol. 2018 Mar;256(3):599-610. doi: 10.1007/s00417-017-3874-8. Epub 2018 Jan 5.
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Comparing optical coherence tomography radial and cube scan patterns for measuring Bruch's membrane opening minimum rim width (BMO-MRW) in glaucoma and healthy eyes: cross-sectional and longitudinal analysis.比较光学相干断层扫描径向和立方扫描模式测量青光眼和正常眼中的 Bruch 膜开口最小边缘宽度(BMO-MRW):横断面和纵向分析。
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Influence of uveitis on Bruch's membrane opening minimum rim width and retinal nerve fibre layer thickness measurements.葡萄膜炎对布鲁赫膜最小开口边缘宽度和视网膜神经纤维层厚度测量的影响。
Br J Ophthalmol. 2019 Oct;103(10):1413-1417. doi: 10.1136/bjophthalmol-2018-313016. Epub 2018 Dec 18.
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Lamina cribrosa position and Bruch's membrane opening differences between anterior ischemic optic neuropathy and open-angle glaucoma.前部缺血性视神经病变与开角型青光眼之间的筛板位置及布鲁赫膜开口差异
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Intra- and interobserver reproducibility of Bruch's membrane opening minimum rim width measurements with spectral domain optical coherence tomography.使用光谱域光学相干断层扫描测量布鲁赫膜开口最小边缘宽度的观察者内和观察者间的可重复性。
Acta Ophthalmol. 2017 Nov;95(7):e548-e555. doi: 10.1111/aos.13464. Epub 2017 Jun 26.

引用本文的文献

1
Non-arteritic anterior ischemic and glaucomatous optic neuropathy: Implications for neuroretinal rim remodeling with disease severity.非动脉炎性前部缺血性视神经病变和青光眼性视神经病变:与疾病严重程度相关的神经视网膜 rim 重塑的意义。
PLoS One. 2023 May 18;18(5):e0286007. doi: 10.1371/journal.pone.0286007. eCollection 2023.
2
Automated macular segmentation can distinguish glaucomatous from compressive optic neuropathy.自动黄斑分割可区分青光眼和压迫性视神经病变。
Graefes Arch Clin Exp Ophthalmol. 2023 Jun;261(6):1701-1712. doi: 10.1007/s00417-022-05962-6. Epub 2023 Jan 10.

本文引用的文献

1
Optic nerve head morphology in primary open-angle glaucoma and nonarteritic anterior ischaemic optic neuropathy measured with spectral domain optical coherence tomography.应用谱域光学相干断层扫描测量原发性开角型青光眼和非动脉炎性前部缺血性视神经病变的视神经头形态。
Acta Ophthalmol. 2018 Dec;96(8):e1018-e1024. doi: 10.1111/aos.13804. Epub 2018 Sep 21.
2
The Relationship Between Bruch's Membrane Opening-Minimum Rim Width and Retinal Nerve Fiber Layer Thickness and a New Index Using a Neural Network.布鲁赫膜开口-最小边缘宽度与视网膜神经纤维层厚度之间的关系以及一种使用神经网络的新指标
Transl Vis Sci Technol. 2018 Aug 24;7(4):14. doi: 10.1167/tvst.7.4.14. eCollection 2018 Aug.
3
Lamina cribrosa position and Bruch's membrane opening differences between anterior ischemic optic neuropathy and open-angle glaucoma.前部缺血性视神经病变与开角型青光眼之间的筛板位置及布鲁赫膜开口差异
Eur J Ophthalmol. 2019 Mar;29(2):202-209. doi: 10.1177/1120672118782101. Epub 2018 Jun 18.
4
Bruch's membrane opening-minimum rim width and visual field loss in glaucoma: a broken stick analysis.青光眼患者的布鲁赫膜开口最小边缘宽度与视野缺损:折断木棍分析
Int J Ophthalmol. 2018 May 18;11(5):828-834. doi: 10.18240/ijo.2018.05.19. eCollection 2018.
5
The role of Optical Coherence Tomography in optic neuropathies.光学相干断层扫描在视神经病变中的作用。
Rom J Ophthalmol. 2018 Jan-Mar;62(1):3-14.
6
Association of Bruch's membrane opening and optic disc morphology to axial length and visual field defects in eyes with primary open-angle glaucoma.原发性开角型青光眼患者眼中布鲁赫膜开口及视盘形态与眼轴长度和视野缺损的相关性
Graefes Arch Clin Exp Ophthalmol. 2018 Mar;256(3):599-610. doi: 10.1007/s00417-017-3874-8. Epub 2018 Jan 5.
7
Neuroimaging diagnostic and monitoring approaches in ophthalmology.神经影像学在眼科学中的诊断和监测方法。
Curr Opin Neurol. 2018 Feb;31(1):66-73. doi: 10.1097/WCO.0000000000000518.
8
Structure-function relationship comparison between retinal nerve fibre layer and Bruch's membrane opening-minimum rim width in glaucoma.青光眼患者视网膜神经纤维层与布鲁赫膜开口-最小边缘宽度之间的结构-功能关系比较
Int J Ophthalmol. 2017 Oct 18;10(10):1534-1538. doi: 10.18240/ijo.2017.10.09. eCollection 2017.
9
Intraday Repeatability of Bruch's Membrane Opening-Based Neuroretinal Rim Measurements.基于布鲁赫膜开口的神经视网膜边缘测量的日内重复性
Invest Ophthalmol Vis Sci. 2017 Oct 1;58(12):5195-5200. doi: 10.1167/iovs.17-22812.
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Ganglion cell layer complex measurements in compressive optic neuropathy.压迫性视神经病变中神经节细胞层复合体测量
Curr Opin Ophthalmol. 2017 Nov;28(6):573-578. doi: 10.1097/ICU.0000000000000428.