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主动脉瓣和二尖瓣手术治疗感染性心内膜炎并重建瓣间纤维体:临床结果分析

Aortic and mitral valve surgery for infective endocarditis with reconstruction of the intervalvular fibrous body: an analysis of clinical outcomes.

作者信息

Jiang Xuan, Liu Jinduo, Khan Fareed, Tang Rui, Zhang Yuhai, Gu Tianxiang

机构信息

Department of Cardiac Surgery, First Affiliated Hospital, China Medical University, Shenyang 110001, China.

出版信息

J Thorac Dis. 2020 Apr;12(4):1427-1436. doi: 10.21037/jtd.2020.03.04.

DOI:10.21037/jtd.2020.03.04
PMID:32395280
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7212136/
Abstract

BACKGROUND

Reconstruction of the aorto-mitral curtain (AMC) for invasive double-valve infective endocarditis (IE) is a rare and challenging procedure. This study presents the short- and mid-term results of reconstruction of AMC in a single center.

METHODS

From 2016 to 2019, 14 patients with invasive double-valve underwent surgical reconstruction of the AMC, along with either double valve replacement or aortic valve replacement with mitral valve repair. Two patients were diagnosed as Behcet's disease. Bicuspid aortic valve was detected in six patients. Mean follow up was 18.9±12.2 months.

RESULTS

Positive blood culture was found in 10 (71.4%) patients: 3 of (21.4%). The mean cardiopulmonary bypass (CPB) time was 154.5±25.9 minutes and the mean cross-clamp time was 116.8±18.2 minutes. One patient died of multiple organ failure (7.1%) 60 days after surgery. There was 1 (7.1%) case of stroke, 1 (7.1%) of atrioventricular block with pacemaker implantation, 1 (7.1%) of reoperation for bleeding. There was no late death during follow-up. The survival at 3 years was 92.9%. Freedom from reoperation at 1, 2, and 3 years was 100%, 100%, and 100% during follow-up, respectively.

CONCLUSIONS

The double-valve replacement and AMC reconstruction (the Commando procedure) is an effective technique in complex heart valve disease. The short- and mid-term results with this technique are optimal, with a very low in-hospital mortality and nearly 100% of long-term survival during follow-up.

摘要

背景

侵袭性双瓣膜感染性心内膜炎(IE)的主动脉-二尖瓣幕重建术(AMC)是一种罕见且具有挑战性的手术。本研究展示了单中心AMC重建术的短期和中期结果。

方法

2016年至2019年,14例侵袭性双瓣膜患者接受了AMC手术重建,同时进行双瓣膜置换或主动脉瓣置换并二尖瓣修复。2例患者被诊断为白塞病。6例患者检测出二叶式主动脉瓣。平均随访时间为18.9±12.2个月。

结果

10例(71.4%)患者血培养呈阳性:其中3例(21.4%)。平均体外循环(CPB)时间为154.5±25.9分钟,平均主动脉阻断时间为116.8±18.2分钟。1例患者术后60天死于多器官功能衰竭(7.1%)。有1例(7.1%)发生中风,1例(7.1%)植入起搏器治疗房室传导阻滞,1例(7.1%)因出血再次手术。随访期间无晚期死亡。3年生存率为92.9%。随访期间1年、2年和3年免于再次手术率分别为100%、100%和100%。

结论

双瓣膜置换和AMC重建术(突击手术)是治疗复杂心脏瓣膜病的有效技术。该技术的短期和中期结果最佳,住院死亡率极低,随访期间长期生存率接近100%。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5852/7212136/a98a0b5c005a/jtd-12-04-1427-f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5852/7212136/43154ee116b9/jtd-12-04-1427-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5852/7212136/9c64f1188eb5/jtd-12-04-1427-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5852/7212136/8ad26c56e75a/jtd-12-04-1427-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5852/7212136/34743d27e8b1/jtd-12-04-1427-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5852/7212136/a98a0b5c005a/jtd-12-04-1427-f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5852/7212136/43154ee116b9/jtd-12-04-1427-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5852/7212136/9c64f1188eb5/jtd-12-04-1427-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5852/7212136/8ad26c56e75a/jtd-12-04-1427-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5852/7212136/34743d27e8b1/jtd-12-04-1427-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5852/7212136/a98a0b5c005a/jtd-12-04-1427-f5.jpg

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