Moradinazar Mehdi, Najafi Farid, Nazar Zeinab Moradi, Hamzeh Behrooz, Pasdar Yahya, Shakiba Ebrahim
Research Center for Environmental Determinants of Health (RCEDH), Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.
J Pregnancy. 2020 Apr 27;2020:4871494. doi: 10.1155/2020/4871494. eCollection 2020.
10-20% of pregnancies end due to spontaneous abortions. In recent years, nondocumentary evidence has been indicative of an increase in the prevalence of nonspontaneous abortions in Iran, especially in the Kurdish regions. The aim of this study is to assess the lifetime prevalence of spontaneous abortions and factors affecting spontaneous abortion in women 35-65 years old.
Data from the recruitment phase of Ravansar Non-Communicable Disease (RaNCD) cohort study was used. All of the 4831 married women 35-65 years old and with history of pregnancy were included in this study. In order to determine the abortion ratio, the number of abortions was divided by the number of live births, and multiple logistic regression analysis was applied to determine associated factors affecting abortion.
About 25.7% of women had a history of spontaneous abortion. The abortion ratio in women was 0.10. The abortion ratio in women with secondary education, first pregnancy and marriage age at ≥26, socioeconomic condition, and hyperthyroid and diabetes was high while the abortion ratio of women with high physical activity and BMI < 18.9 or residents of rural area was low. After assessing the effective variables, it was found that women with high blood pressure have 63% less odds for nonspontaneous abortion, which is statistically significant ( value < 0.05).
Considering the effect of factors such as level of education, older age at the first marriage, and age at the first pregnancy on increased chance of spontaneous abortion, measures should be taken to take more care for these people.
10%-20%的妊娠以自然流产告终。近年来，非文献证据表明伊朗非自然流产的患病率有所上升，尤其是在库尔德地区。本研究的目的是评估35-65岁女性自然流产的终生患病率以及影响自然流产的因素。
使用了拉万萨尔非传染性疾病（RaNCD）队列研究招募阶段的数据。本研究纳入了所有4831名年龄在35-65岁且有妊娠史的已婚女性。为了确定流产率，将流产次数除以活产次数，并应用多元逻辑回归分析来确定影响流产的相关因素。
约25.7%的女性有自然流产史。女性的流产率为0.10。受过中等教育、首次怀孕且结婚年龄≥26岁、社会经济状况以及患有甲状腺功能亢进和糖尿病的女性流产率较高，而身体活动量高且BMI<18.9的女性或农村地区居民的流产率较低。在评估有效变量后发现，患有高血压的女性非自然流产的几率降低63%，这具有统计学意义（P值<0.05）。
考虑到教育水平、初婚年龄较大和首次怀孕年龄等因素对自然流产几率增加的影响，应采取措施对这些人群给予更多关注。
