The Ekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, Ekaterinburg, Russia.
The Central Research Laboratory, Ural Medical University, Ekaterinburg, Russia.
Nanotoxicology. 2020 Aug;14(6):788-806. doi: 10.1080/17435390.2020.1762132. Epub 2020 May 12.
Over the past few years, the Ekaterinburg (Russia) interdisciplinary nanotoxicological research team has carried out a series of investigations using different and experimental models in order to elucidate the cytotoxicity and organ-systemic and organism-level toxicity of lead-containing nanoparticles (NP) acting separately or in combinations with some other metallic NPs. The authors claim that their many-sided experience in this field is unique and that some of their important results have been obtained for the first time. This paper is an overview of the team's previous publications in different journals. It is suggested to be used as a compact scientific base for assessing health risks associated not only with the production and usage of engineered lead-containing NPs but also with their inevitable by-production as toxic air pollutants in the metallurgy of lead, copper or their alloys and in soldering operations.
在过去的几年中，叶卡捷琳堡（俄罗斯）跨学科纳米毒理学研究团队使用不同的实验模型进行了一系列研究，旨在阐明含铅纳米颗粒（NP）的细胞毒性以及在单独或与其他一些金属 NP 联合作用下对器官系统和生物体水平的毒性。作者声称，他们在该领域的多方面经验是独一无二的，并且他们的一些重要结果是首次获得的。本文概述了该团队在不同期刊上的以往出版物。建议将其用作评估健康风险的紧凑科学基础，这些风险不仅与含铅工程纳米颗粒的生产和使用有关，而且还与它们作为铅、铜或其合金冶金和焊接操作中的有毒空气污染物不可避免的副产物有关。
